pH-Sensitive Nanoparticles Codelivering Docetaxel and Dihydroartemisinin Effectively Treat Breast Cancer by Enhancing Reactive Oxidative Species-Mediated Mitochondrial Apoptosis

Tumor growth and metastasis are the major causes of high mortality in breast cancer. We previously constructed pH-sensitive nanoparticles (D/D NPs) for the codelivery of docetaxel (DTX) and dihydroartemisinin (DHA) and demonstrated that D/D NPs showed anticancer activity in breast cancer cells in vi...

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Veröffentlicht in:	Molecular pharmaceutics 2021-01, Vol.18 (1), p.74-86
Hauptverfasser:	Tao, Jin, Diao, Lu, Chen, Fangcheng, Shen, Ao, Wang, Shutian, Jin, Hongyan, Cai, Danwei, Hu, Ying
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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