Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses
Background Cutting needles are thought to be effective as biopsy needles. A few types of cutting needles are available for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and the Menghini-type needle is an end-type cutting needle. Aims A prospective randomized controlled trial was con...
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Veröffentlicht in: | Digestive diseases and sciences 2021-09, Vol.66 (9), p.3171-3178 |
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creator | Mizukawa, Sho Kato, Hironari Matsumoto, Kazuyuki Muro, Shinichiro Akimoto, Yutaka Uchida, Daisuke Tomoda, Takeshi Yamamoto, Naoki Horiguchi, Shigeru Tsutsumi, Koichiro Inoue, Hirofumi Tanaka, Noriyuki Okada, Hiroyuki |
description | Background
Cutting needles are thought to be effective as biopsy needles. A few types of cutting needles are available for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and the Menghini-type needle is an end-type cutting needle.
Aims
A prospective randomized controlled trial was conducted to compare the results of EUS-FNA using a Menghini-type needle (needle M) versus a conventional needle (needle S).
Methods
The main eligibility criteria were as follows: patients with a pancreatic mass referred for EUS-FNA, ≥ 20 years old, and a performance status |
doi_str_mv | 10.1007/s10620-020-06628-1 |
format | Article |
fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2452501937</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A712933297</galeid><sourcerecordid>A712933297</sourcerecordid><originalsourceid>FETCH-LOGICAL-c442t-8bc7d4395bb46e04847bd109818a8d74711ef04ddd0befb1a59974db465199563</originalsourceid><addsrcrecordid>eNp9kU1rFTEUhoMo9lr9Ay5kwI2bqfmaZLK8lNsqtOqiXYdMcnJNmZuMyZ1C_70ZploUkXDI1_O-nORF6C3BZwRj-bEQLChu8VJC0L4lz9CGdJK1tBP9c7TBRNQ1IeIEvSrlDmOsJBEv0QljWPaM0g0qO-_BHsM9RCilSb65hrj_HmJobx4maL4AuBFK41NudtGlYtMUbHM7HrMpaY6uvZyDA9dchAjtSjfbMoVsjiHFxfCbiTZD3drm2pQC5TV64c1Y4M3jfIpuL3Y355_aq6-Xn8-3V63lnB7bfrDScaa6YeACMO-5HBzBqie96Z3kkhDwmDvn8AB-IKZTSnJX4Y4o1Ql2ij6svlNOP2YoR30IxcI4mghpLpryjnaYKCYr-v4v9C7NOdbudP1LhgUjQjxRezOCDtGn-gt2MdVbSahijKrF6-wfVB0ODsGmCD7U8z8EdBXYnErJ4PWUw8HkB02wXpLWa9IaL7UkrUkVvXvseB4O4H5LfkVbAbYCpV7FPeSnJ_3H9ic8GrGc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2563063166</pqid></control><display><type>article</type><title>Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Mizukawa, Sho ; Kato, Hironari ; Matsumoto, Kazuyuki ; Muro, Shinichiro ; Akimoto, Yutaka ; Uchida, Daisuke ; Tomoda, Takeshi ; Yamamoto, Naoki ; Horiguchi, Shigeru ; Tsutsumi, Koichiro ; Inoue, Hirofumi ; Tanaka, Noriyuki ; Okada, Hiroyuki</creator><creatorcontrib>Mizukawa, Sho ; Kato, Hironari ; Matsumoto, Kazuyuki ; Muro, Shinichiro ; Akimoto, Yutaka ; Uchida, Daisuke ; Tomoda, Takeshi ; Yamamoto, Naoki ; Horiguchi, Shigeru ; Tsutsumi, Koichiro ; Inoue, Hirofumi ; Tanaka, Noriyuki ; Okada, Hiroyuki</creatorcontrib><description>Background
Cutting needles are thought to be effective as biopsy needles. A few types of cutting needles are available for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and the Menghini-type needle is an end-type cutting needle.
Aims
A prospective randomized controlled trial was conducted to compare the results of EUS-FNA using a Menghini-type needle (needle M) versus a conventional needle (needle S).
Methods
The main eligibility criteria were as follows: patients with a pancreatic mass referred for EUS-FNA, ≥ 20 years old, and a performance status < 4. The primary outcome was the sample quality. The secondary outcomes were factors associated with the sample quality, diagnostic accuracy, and adverse events.
Results
A total of 97 patients were enrolled in this study. The sample quality for total puncture with needle M (92.8%) was significantly higher than that with needle S (81.4%) (
p
= 0.0305). The tumor size (
p
= 0.033) and type of needle (
p
= 0.031) were significant factors associated with adequate tissue collection in univariate and multivariate analyses (odds ratio [OR] 2.71; 95% confidence interval [CI] 1.12–6.54;
p
= 0.027 for tumor size, and OR 2.93; 95% CI 1.23–8.21;
p
= 0.0153 for type of needle). The diagnostic accuracy of each needle was 88.7% (86/97) with needle M and 73.2% (71/97) with needle S. Adverse events occurred in 2 of the 97 patients (0.02%).
Conclusion
A Menghini-type needle was able to obtain core tissue for histology more effectively than a conventional aspiration needle.
Trial Registration Numbers
UMIN registration number of 000020668.</description><identifier>ISSN: 0163-2116</identifier><identifier>EISSN: 1573-2568</identifier><identifier>DOI: 10.1007/s10620-020-06628-1</identifier><identifier>PMID: 33078322</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aged ; Analysis ; Biochemistry ; Cross-Over Studies ; Diagnosis, Differential ; Endoscopic ultrasonography ; Endoscopic Ultrasound-Guided Fine Needle Aspiration - adverse effects ; Endoscopic Ultrasound-Guided Fine Needle Aspiration - instrumentation ; Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods ; Endoscopy ; Equipment Design ; Female ; Gastroenterology ; Hepatology ; Humans ; Male ; Materials Testing - methods ; Medical research ; Medicine ; Medicine & Public Health ; Medicine, Experimental ; Needles - adverse effects ; Oncology ; Original Article ; Outcome and Process Assessment, Health Care - methods ; Pancreatic cancer ; Pancreatic Neoplasms - diagnostic imaging ; Pancreatic Neoplasms - pathology ; Specimen Handling - methods ; Specimen Handling - standards ; Transplant Surgery ; Ultrasonic imaging ; UMIN</subject><ispartof>Digestive diseases and sciences, 2021-09, Vol.66 (9), p.3171-3178</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>2020. Springer Science+Business Media, LLC, part of Springer Nature.</rights><rights>COPYRIGHT 2021 Springer</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-8bc7d4395bb46e04847bd109818a8d74711ef04ddd0befb1a59974db465199563</citedby><cites>FETCH-LOGICAL-c442t-8bc7d4395bb46e04847bd109818a8d74711ef04ddd0befb1a59974db465199563</cites><orcidid>0000-0003-1120-292X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10620-020-06628-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10620-020-06628-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33078322$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mizukawa, Sho</creatorcontrib><creatorcontrib>Kato, Hironari</creatorcontrib><creatorcontrib>Matsumoto, Kazuyuki</creatorcontrib><creatorcontrib>Muro, Shinichiro</creatorcontrib><creatorcontrib>Akimoto, Yutaka</creatorcontrib><creatorcontrib>Uchida, Daisuke</creatorcontrib><creatorcontrib>Tomoda, Takeshi</creatorcontrib><creatorcontrib>Yamamoto, Naoki</creatorcontrib><creatorcontrib>Horiguchi, Shigeru</creatorcontrib><creatorcontrib>Tsutsumi, Koichiro</creatorcontrib><creatorcontrib>Inoue, Hirofumi</creatorcontrib><creatorcontrib>Tanaka, Noriyuki</creatorcontrib><creatorcontrib>Okada, Hiroyuki</creatorcontrib><title>Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses</title><title>Digestive diseases and sciences</title><addtitle>Dig Dis Sci</addtitle><addtitle>Dig Dis Sci</addtitle><description>Background
Cutting needles are thought to be effective as biopsy needles. A few types of cutting needles are available for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and the Menghini-type needle is an end-type cutting needle.
Aims
A prospective randomized controlled trial was conducted to compare the results of EUS-FNA using a Menghini-type needle (needle M) versus a conventional needle (needle S).
Methods
The main eligibility criteria were as follows: patients with a pancreatic mass referred for EUS-FNA, ≥ 20 years old, and a performance status < 4. The primary outcome was the sample quality. The secondary outcomes were factors associated with the sample quality, diagnostic accuracy, and adverse events.
Results
A total of 97 patients were enrolled in this study. The sample quality for total puncture with needle M (92.8%) was significantly higher than that with needle S (81.4%) (
p
= 0.0305). The tumor size (
p
= 0.033) and type of needle (
p
= 0.031) were significant factors associated with adequate tissue collection in univariate and multivariate analyses (odds ratio [OR] 2.71; 95% confidence interval [CI] 1.12–6.54;
p
= 0.027 for tumor size, and OR 2.93; 95% CI 1.23–8.21;
p
= 0.0153 for type of needle). The diagnostic accuracy of each needle was 88.7% (86/97) with needle M and 73.2% (71/97) with needle S. Adverse events occurred in 2 of the 97 patients (0.02%).
Conclusion
A Menghini-type needle was able to obtain core tissue for histology more effectively than a conventional aspiration needle.
Trial Registration Numbers
UMIN registration number of 000020668.</description><subject>Aged</subject><subject>Analysis</subject><subject>Biochemistry</subject><subject>Cross-Over Studies</subject><subject>Diagnosis, Differential</subject><subject>Endoscopic ultrasonography</subject><subject>Endoscopic Ultrasound-Guided Fine Needle Aspiration - adverse effects</subject><subject>Endoscopic Ultrasound-Guided Fine Needle Aspiration - instrumentation</subject><subject>Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods</subject><subject>Endoscopy</subject><subject>Equipment Design</subject><subject>Female</subject><subject>Gastroenterology</subject><subject>Hepatology</subject><subject>Humans</subject><subject>Male</subject><subject>Materials Testing - methods</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Needles - adverse effects</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Outcome and Process Assessment, Health Care - methods</subject><subject>Pancreatic cancer</subject><subject>Pancreatic Neoplasms - diagnostic imaging</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Specimen Handling - methods</subject><subject>Specimen Handling - standards</subject><subject>Transplant Surgery</subject><subject>Ultrasonic imaging</subject><subject>UMIN</subject><issn>0163-2116</issn><issn>1573-2568</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kU1rFTEUhoMo9lr9Ay5kwI2bqfmaZLK8lNsqtOqiXYdMcnJNmZuMyZ1C_70ZploUkXDI1_O-nORF6C3BZwRj-bEQLChu8VJC0L4lz9CGdJK1tBP9c7TBRNQ1IeIEvSrlDmOsJBEv0QljWPaM0g0qO-_BHsM9RCilSb65hrj_HmJobx4maL4AuBFK41NudtGlYtMUbHM7HrMpaY6uvZyDA9dchAjtSjfbMoVsjiHFxfCbiTZD3drm2pQC5TV64c1Y4M3jfIpuL3Y355_aq6-Xn8-3V63lnB7bfrDScaa6YeACMO-5HBzBqie96Z3kkhDwmDvn8AB-IKZTSnJX4Y4o1Ql2ij6svlNOP2YoR30IxcI4mghpLpryjnaYKCYr-v4v9C7NOdbudP1LhgUjQjxRezOCDtGn-gt2MdVbSahijKrF6-wfVB0ODsGmCD7U8z8EdBXYnErJ4PWUw8HkB02wXpLWa9IaL7UkrUkVvXvseB4O4H5LfkVbAbYCpV7FPeSnJ_3H9ic8GrGc</recordid><startdate>20210901</startdate><enddate>20210901</enddate><creator>Mizukawa, Sho</creator><creator>Kato, Hironari</creator><creator>Matsumoto, Kazuyuki</creator><creator>Muro, Shinichiro</creator><creator>Akimoto, Yutaka</creator><creator>Uchida, Daisuke</creator><creator>Tomoda, Takeshi</creator><creator>Yamamoto, Naoki</creator><creator>Horiguchi, Shigeru</creator><creator>Tsutsumi, Koichiro</creator><creator>Inoue, Hirofumi</creator><creator>Tanaka, Noriyuki</creator><creator>Okada, Hiroyuki</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1120-292X</orcidid></search><sort><creationdate>20210901</creationdate><title>Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses</title><author>Mizukawa, Sho ; Kato, Hironari ; Matsumoto, Kazuyuki ; Muro, Shinichiro ; Akimoto, Yutaka ; Uchida, Daisuke ; Tomoda, Takeshi ; Yamamoto, Naoki ; Horiguchi, Shigeru ; Tsutsumi, Koichiro ; Inoue, Hirofumi ; Tanaka, Noriyuki ; Okada, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-8bc7d4395bb46e04847bd109818a8d74711ef04ddd0befb1a59974db465199563</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Analysis</topic><topic>Biochemistry</topic><topic>Cross-Over Studies</topic><topic>Diagnosis, Differential</topic><topic>Endoscopic ultrasonography</topic><topic>Endoscopic Ultrasound-Guided Fine Needle Aspiration - adverse effects</topic><topic>Endoscopic Ultrasound-Guided Fine Needle Aspiration - instrumentation</topic><topic>Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods</topic><topic>Endoscopy</topic><topic>Equipment Design</topic><topic>Female</topic><topic>Gastroenterology</topic><topic>Hepatology</topic><topic>Humans</topic><topic>Male</topic><topic>Materials Testing - methods</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Needles - adverse effects</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Outcome and Process Assessment, Health Care - methods</topic><topic>Pancreatic cancer</topic><topic>Pancreatic Neoplasms - diagnostic imaging</topic><topic>Pancreatic Neoplasms - pathology</topic><topic>Specimen Handling - methods</topic><topic>Specimen Handling - standards</topic><topic>Transplant Surgery</topic><topic>Ultrasonic imaging</topic><topic>UMIN</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mizukawa, Sho</creatorcontrib><creatorcontrib>Kato, Hironari</creatorcontrib><creatorcontrib>Matsumoto, Kazuyuki</creatorcontrib><creatorcontrib>Muro, Shinichiro</creatorcontrib><creatorcontrib>Akimoto, Yutaka</creatorcontrib><creatorcontrib>Uchida, Daisuke</creatorcontrib><creatorcontrib>Tomoda, Takeshi</creatorcontrib><creatorcontrib>Yamamoto, Naoki</creatorcontrib><creatorcontrib>Horiguchi, Shigeru</creatorcontrib><creatorcontrib>Tsutsumi, Koichiro</creatorcontrib><creatorcontrib>Inoue, Hirofumi</creatorcontrib><creatorcontrib>Tanaka, Noriyuki</creatorcontrib><creatorcontrib>Okada, Hiroyuki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Digestive diseases and sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mizukawa, Sho</au><au>Kato, Hironari</au><au>Matsumoto, Kazuyuki</au><au>Muro, Shinichiro</au><au>Akimoto, Yutaka</au><au>Uchida, Daisuke</au><au>Tomoda, Takeshi</au><au>Yamamoto, Naoki</au><au>Horiguchi, Shigeru</au><au>Tsutsumi, Koichiro</au><au>Inoue, Hirofumi</au><au>Tanaka, Noriyuki</au><au>Okada, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses</atitle><jtitle>Digestive diseases and sciences</jtitle><stitle>Dig Dis Sci</stitle><addtitle>Dig Dis Sci</addtitle><date>2021-09-01</date><risdate>2021</risdate><volume>66</volume><issue>9</issue><spage>3171</spage><epage>3178</epage><pages>3171-3178</pages><issn>0163-2116</issn><eissn>1573-2568</eissn><abstract>Background
Cutting needles are thought to be effective as biopsy needles. A few types of cutting needles are available for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), and the Menghini-type needle is an end-type cutting needle.
Aims
A prospective randomized controlled trial was conducted to compare the results of EUS-FNA using a Menghini-type needle (needle M) versus a conventional needle (needle S).
Methods
The main eligibility criteria were as follows: patients with a pancreatic mass referred for EUS-FNA, ≥ 20 years old, and a performance status < 4. The primary outcome was the sample quality. The secondary outcomes were factors associated with the sample quality, diagnostic accuracy, and adverse events.
Results
A total of 97 patients were enrolled in this study. The sample quality for total puncture with needle M (92.8%) was significantly higher than that with needle S (81.4%) (
p
= 0.0305). The tumor size (
p
= 0.033) and type of needle (
p
= 0.031) were significant factors associated with adequate tissue collection in univariate and multivariate analyses (odds ratio [OR] 2.71; 95% confidence interval [CI] 1.12–6.54;
p
= 0.027 for tumor size, and OR 2.93; 95% CI 1.23–8.21;
p
= 0.0153 for type of needle). The diagnostic accuracy of each needle was 88.7% (86/97) with needle M and 73.2% (71/97) with needle S. Adverse events occurred in 2 of the 97 patients (0.02%).
Conclusion
A Menghini-type needle was able to obtain core tissue for histology more effectively than a conventional aspiration needle.
Trial Registration Numbers
UMIN registration number of 000020668.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33078322</pmid><doi>10.1007/s10620-020-06628-1</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-1120-292X</orcidid></addata></record> |
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source | MEDLINE; Springer Nature - Complete Springer Journals |
subjects | Aged Analysis Biochemistry Cross-Over Studies Diagnosis, Differential Endoscopic ultrasonography Endoscopic Ultrasound-Guided Fine Needle Aspiration - adverse effects Endoscopic Ultrasound-Guided Fine Needle Aspiration - instrumentation Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods Endoscopy Equipment Design Female Gastroenterology Hepatology Humans Male Materials Testing - methods Medical research Medicine Medicine & Public Health Medicine, Experimental Needles - adverse effects Oncology Original Article Outcome and Process Assessment, Health Care - methods Pancreatic cancer Pancreatic Neoplasms - diagnostic imaging Pancreatic Neoplasms - pathology Specimen Handling - methods Specimen Handling - standards Transplant Surgery Ultrasonic imaging UMIN |
title | Effectiveness of Menghini-Type Needles for Endoscopic Ultrasound-Guided Fine-Needle Aspiration of Pancreatic Masses |
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