Intracellular zinc-dependent TAS2R8 gene expression through CTCF activation

Taste-2 receptors (TAS2Rs), which belong to the G-protein coupled receptor (GPCR) family, are receptors for bitter taste perception. The aim of this study was to investigate whether zinc deficiency affects the expression of TAS2R genes. The promoter activity of the TAS2R7, TAS2R8, and TAS2R42 genes...

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Veröffentlicht in:	Biomedical Research 2020/10/16, Vol.41(5), pp.217-225
Hauptverfasser:	KOJIMA, Tsuyoshi, MAEDA, Toyonobu, SUZUKI, Atsuko, YAMAMORI, Tetsuo, KATO, Yasumasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Bitter taste Chromatin Deletion mutant Deprivation G protein-coupled receptors Gene deletion Gene expression Genes Immunoprecipitation Intracellular Nucleotides Nutrient deficiency Oral squamous cell carcinoma Receptors Squamous cell carcinoma Taste Taste perception Taste receptors Zinc
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