Endoscopic treatments for GERD
Gastroesophageal reflux disease (GERD) is a condition with increasing prevalence and morbidity in the United States and worldwide. Despite advances in medical and surgical therapy over the last 30 years, gaps remain in the therapeutic profile of options. Flexible upper endoscopy offers the promise o...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 2020-12, Vol.1482 (1), p.121-129 |
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| creator | Kushner, Bradley S. Awad, Michael M. Mikami, Dean J. Chand, Bipan B. Wai, Christina J. Murayama, Kenric M. |
| description | Gastroesophageal reflux disease (GERD) is a condition with increasing prevalence and morbidity in the United States and worldwide. Despite advances in medical and surgical therapy over the last 30 years, gaps remain in the therapeutic profile of options. Flexible upper endoscopy offers the promise of filling in these gaps in a potentially minimally invasive approach. In this concise review, we focus on the plethora of endoluminal therapies available for the treatment of GERD. Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. As new endoscopic treatments become available, we come closer to the promise of the incisionless treatment of GERD. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.
In this concise review, we discuss the plethora of endoluminal therapies available for the treatment of gastroesophageal reflux disease (GERD). Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail. |
| doi_str_mv | 10.1111/nyas.14511 |
| format | Article |
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In this concise review, we discuss the plethora of endoluminal therapies available for the treatment of gastroesophageal reflux disease (GERD). Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.</description><identifier>ISSN: 0077-8923</identifier><identifier>EISSN: 1749-6632</identifier><identifier>DOI: 10.1111/nyas.14511</identifier><identifier>PMID: 33063344</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Ablation ; Electric Stimulation - methods ; Electrical stimuli ; emerging technology ; endoscopic therapy ; Endoscopy ; Esophageal sphincter ; Esophageal Sphincter, Lower - physiopathology ; Esophagoscopy - methods ; Esophagus ; flexible endoscopy ; Fundoplication - methods ; Gastroesophageal reflux ; Gastroesophageal Reflux - therapy ; GERD ; Health services ; Humans ; Medical treatment ; Morbidity ; Polyvinyls - therapeutic use ; Radio frequency ; Radiofrequency ablation ; Radiofrequency Ablation - methods ; Sphincter</subject><ispartof>Annals of the New York Academy of Sciences, 2020-12, Vol.1482 (1), p.121-129</ispartof><rights>2020 New York Academy of Sciences.</rights><rights>2020 The New York Academy of Sciences</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3571-9a03c777a631edc4504a511c64c9c223aa95a9eb6019ca2d91fe4781ea63aa5a3</citedby><cites>FETCH-LOGICAL-c3571-9a03c777a631edc4504a511c64c9c223aa95a9eb6019ca2d91fe4781ea63aa5a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fnyas.14511$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fnyas.14511$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33063344$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kushner, Bradley S.</creatorcontrib><creatorcontrib>Awad, Michael M.</creatorcontrib><creatorcontrib>Mikami, Dean J.</creatorcontrib><creatorcontrib>Chand, Bipan B.</creatorcontrib><creatorcontrib>Wai, Christina J.</creatorcontrib><creatorcontrib>Murayama, Kenric M.</creatorcontrib><title>Endoscopic treatments for GERD</title><title>Annals of the New York Academy of Sciences</title><addtitle>Ann N Y Acad Sci</addtitle><description>Gastroesophageal reflux disease (GERD) is a condition with increasing prevalence and morbidity in the United States and worldwide. Despite advances in medical and surgical therapy over the last 30 years, gaps remain in the therapeutic profile of options. Flexible upper endoscopy offers the promise of filling in these gaps in a potentially minimally invasive approach. In this concise review, we focus on the plethora of endoluminal therapies available for the treatment of GERD. Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. As new endoscopic treatments become available, we come closer to the promise of the incisionless treatment of GERD. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.
In this concise review, we discuss the plethora of endoluminal therapies available for the treatment of gastroesophageal reflux disease (GERD). Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. 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In this concise review, we discuss the plethora of endoluminal therapies available for the treatment of gastroesophageal reflux disease (GERD). Therapies discussed include injectable agents, electrical stimulation of the lower esophageal sphincter, antireflux mucosectomy, radiofrequency ablation, and endoscopic suturing devices designed to create a fundoplication. The known data surrounding the indications, benefits, and risks of these historical, current, and emerging approaches are reviewed in detail.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33063344</pmid><doi>10.1111/nyas.14511</doi><tpages>9</tpages></addata></record> |
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| ispartof | Annals of the New York Academy of Sciences, 2020-12, Vol.1482 (1), p.121-129 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Ablation Electric Stimulation - methods Electrical stimuli emerging technology endoscopic therapy Endoscopy Esophageal sphincter Esophageal Sphincter, Lower - physiopathology Esophagoscopy - methods Esophagus flexible endoscopy Fundoplication - methods Gastroesophageal reflux Gastroesophageal Reflux - therapy GERD Health services Humans Medical treatment Morbidity Polyvinyls - therapeutic use Radio frequency Radiofrequency ablation Radiofrequency Ablation - methods Sphincter |
| title | Endoscopic treatments for GERD |
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