Comprehensive analysis of the expression and prognostic value of CXC chemokines in colorectal cancer

•Highly expressed CXCL1-3, 5, 8 exert an important effect on CRC oncogenesis.•Highly expressed CXCL10-11 serve as positive prognostic factors for CRC patients.•CXCL9-11 may recruit anti-tumor CD8+ T cells and NK cells in CRC patients. The C-X-C motif (CXC) chemokines play an important role in inflam...

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Veröffentlicht in:	International immunopharmacology 2020-12, Vol.89, p.107077-107077, Article 107077
Hauptverfasser:	Yu, Li, Yang, Xinmei, Xu, Chuchu, Sun, Jiachun, Fang, Zhipeng, Pan, Hongming, Han, Weidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Antitumor activity Biomarkers Cancer CD8 antigen Chemokines Colorectal adenocarcinoma Colorectal carcinoma CXC chemokines Immune response Immune system Infiltration Inflammation Lymphocytes Lymphocytes T Medical prognosis Metastases Natural killer cells Prognosis Survival Survival analysis Transcription Tumor-infiltrating immune cells Tumorigenesis
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