Emerging roles of the TRPV4 channel in bladder physiology and dysfunction

The transient receptor potential vanilloid type 4, TRPV4, is a polymodal cation channel which can be activated by diverse stimuli including mechanical, thermal and chemical cues. In the urinary bladder, TRPV4 is not only abundantly expressed in the urothelium but may also be localized in subepitheli...

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Veröffentlicht in:	The Journal of physiology 2021-01, Vol.599 (1), p.39-47
Hauptverfasser:	Wu, Yanyuan, Qi, Jun, Wu, Changhao, Rong, Weifang
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP Bladder Chemical stimuli Contractility mechanosensory transduction Muscle, Smooth Sensory neurons Transient receptor potential proteins TRPV Cation Channels TRPV4 Urinary Bladder Urination Urothelium voiding disorders
Online-Zugang:	Volltext
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