Cellular morphological features are predictive markers of cancer cell state

Even genetically identical cells have heterogeneous properties because of stochasticity in gene or protein expression. Single cell techniques that assay heterogeneous properties would be valuable for basic science and diseases like cancer, where accurate estimates of tumor properties is critical for...

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Veröffentlicht in:	Computers in biology and medicine 2020-11, Vol.126, p.104044-104044, Article 104044
Hauptverfasser:	Alizadeh, Elaheh, Castle, Jordan, Quirk, Analia, Taylor, Cameron D.L., Xu, Wenlong, Prasad, Ashok
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Biomedical materials Biotechnology Bone cancer Breast cancer Cell morphology Cell shape Cytology Cytoskeletal structure Drug resistance Gene expression Genetic transformation Hypotheses Information processing Laboratories Learning algorithms Machine learning Medical imaging Metastases Metastasis Morphology Mutation Parameters Phenotypes Properties (attributes) Signatures Stochasticity Tumorigenesis
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