Integrating genetic and clinical data to predict impulse control disorders in Parkinson's disease

Background and purpose Impulse control disorders (ICDs) are frequent in Parkinson’s disease (PD), with associated clinical and genetic risk factors. This study was aimed at analyzing the clinical features and the genetic background that underlie ICDs in PD. Methods We included 353 patients with PD i...

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Veröffentlicht in:	European journal of neurology 2021-02, Vol.28 (2), p.459-468
Hauptverfasser:	Jesús, S., Periñán, M. T., Cortés, C., Buiza‐Rueda, D., Macías‐García, D., Adarmes, A., Muñoz‐Delgado, L., Labrador‐Espinosa, M. Á., Tejera‐Parrado, C., Gómez‐Garre, M. P., Mir, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic-L-amino-acid decarboxylase DDC Dihydroxyphenylalanine Disease control Disorders dopa decarboxylase gene Dopamine Dopamine receptors dopaminergic pathway genes Genetic factors genetics Glutamatergic transmission Health risk assessment Health services impulse control disorders Impulsive behavior Medical treatment Movement disorders Neurodegenerative diseases Neurotransmitters Nucleotides Obsessive compulsive disorder Opioids Parkinson's disease Patients Risk analysis Risk assessment Risk factors Single-nucleotide polymorphism
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