Recurrence rates in stable bipolar disorder patients after drug discontinuation v. drug maintenance: a systematic review and meta-analysis

This random-effects model meta-analysis of double-blind, randomized placebo-controlled trials compared recurrence rates in bipolar disorder (BD) patients between antipsychotic/mood stabilizer discontinuation and maintenance groups. We conducted systematic literature search of Embase, PubMed, and CEN...

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Veröffentlicht in:	Psychological medicine 2021-11, Vol.51 (15), p.2721-2729
Hauptverfasser:	Kishi, Taro, Matsuda, Yuki, Sakuma, Kenji, Okuya, Makoto, Mishima, Kazuo, Iwata, Nakao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antipsychotic Agents - therapeutic use Antipsychotics Aripiprazole Bipolar disorder Bipolar Disorder - drug therapy Clinical trials Discontinued Double-blind studies Drug abuse Humans Lamotrigine Lithium Mental depression Meta-analysis Mood Olanzapine Original Article Patients Placebos Psychotropic drugs Quetiapine Randomized Controlled Trials as Topic Recurrence Risperidone Systematic review Treatment Outcome Valproic acid
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