Yin Yang 1-induced LINC00667 up-regulates pyruvate dehydrogenase kinase 1 to promote proliferation, migration and invasion of cholangiocarcinoma cells by sponging miR-200c-3p

Cholangiocarcinoma (CCA) is one of the most aggressive and lethal malignancies. Long noncoding RNAs (lncRNAs) are being found to play crucial roles in CCA progression. This work aims to investigate the roles of long intergenic non-protein coding RNA 667 (LINC00667) in progression of CCA. RT-qPCR and...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2021, Vol.34 (1), p.187-200
Hauptverfasser:	Li, Jinglin, Guan, Canghai, Hu, Zengtao, Liu, Lang, Su, Zhilei, Kang, Pengcheng, Jiang, Xingming, Cui, Yunfu
Format:	Artikel
Sprache:	eng
Schlagworte:	Argonaute 2 protein Bile Duct Neoplasms - genetics Bile Duct Neoplasms - pathology Bioinformatics Biomedical and Life Sciences Cell Biology Cell Line, Tumor Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Cholangiocarcinoma Cholangiocarcinoma - genetics Cholangiocarcinoma - pathology Dehydrogenases Gene expression Gene regulation Gynecology Humans Kinases Life Sciences Lymph nodes Medical prognosis Mesenchyme Metastases MicroRNAs - genetics MicroRNAs - metabolism Neoplasm Invasiveness - genetics Oncology Pyruvate Dehydrogenase Acetyl-Transferring Kinase - metabolism Pyruvic acid Reproductive Medicine Research Article RNA, Long Noncoding - physiology RNA-mediated interference Stem Cells Surgery Tumorigenesis Up-Regulation - genetics Xenografts YY1 protein YY1 Transcription Factor - physiology
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