The importance of T cell-derived cytokines in post-kala-azar dermal leishmaniasis

•Th1-, Th17-, and CD8+ cytotoxic T cell-derived cytokines are protective to PKDL.•Inadequate Th1- and Th17-, and CD8+ CTL activity contribute to the PKDL development.•CD4+ Treg-, CD8+ Treg-, and Th2 cell- derived cytokines lead to PKDL development.•IL-10 produce by various cell types playing a key r...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2021-11, Vol.147, p.155321-155321, Article 155321
Hauptverfasser:	Jafarzadeh, Abdollah, Jafarzadeh, Sara, Sharifi, Iraj, Aminizadeh, Najmeh, Nozari, Parvin, Nemati, Maryam
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytokines Cytokines - immunology Humans Immune responses Leishmania donovani Leishmania donovani - immunology Leishmaniasis, Cutaneous - immunology Leishmaniasis, Visceral - immunology Post-kala-azar dermal leishmaniasis T cells T-Lymphocytes - immunology
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