Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy
Objective To compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma. Methods We retrospectively collected data from patients who underwent...
Gespeichert in:
| Veröffentlicht in: | Journal of international medical research 2020-10, Vol.48 (10), p.300060520961238-300060520961238 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 300060520961238 |
|---|---|
| container_issue | 10 |
| container_start_page | 300060520961238 |
| container_title | Journal of international medical research |
| container_volume | 48 |
| creator | Guo, Xudong Wang, Hanbo Xiang, Yuzhu Jin, Xunbo Jiang, Shaobo |
| description | Objective
To compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma.
Methods
We retrospectively collected data from patients who underwent HALRN or LRN for stage ≥T2b renal cell carcinoma from January 2011 to January 2018 in our institution. The patients’ demographics, perioperative parameters, and postoperative follow-up data were compared between the two groups. The survival outcome was estimated using the Kaplan–Meier method.
Results
The HALRN group comprised 78 patients, and the LRN group comprised 63 patients. The median operative duration was significantly shorter in the HALRN than LRN group. The two groups were equivalent in terms of the incision length, blood loss, complication rate, and duration of hospitalization. In the HALRN and LRN groups, the 5-year overall survival rates were 69.4% and 73.1%, the 5-year cancer-specific survival rates were 80.0% and 83.3%, and the 5-year progression-free survival rates were 66.4% and 74.7%, respectively, with no significant differences.
Conclusions
Compared with LRN, HALRN may offer a shorter operative duration and equivalent surgical outcomes without sacrificing oncological efficacy. In addition, HALRN has specific advantages for extremely large and complicated renal tumors. |
| doi_str_mv | 10.1177/0300060520961238 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_proquest_miscellaneous_2449994414</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0300060520961238</sage_id><doaj_id>oai_doaj_org_article_b1665f41670b4cfeb51de4bc53efd49f</doaj_id><sourcerecordid>2456222477</sourcerecordid><originalsourceid>FETCH-LOGICAL-c594t-79cbb99d3327e33533379b3fe811a00764be04b094f5f355a8458722558dd71e3</originalsourceid><addsrcrecordid>eNp1kkuOEzEQhlsIxISBPSvUEpth0eBnO2aBhEY8RhqJBcPa8qOcOOq2g90ZlCNwEM7BXTgJTjIMZCQ2tlz1_5_tqmqapxi9xFiIV4gihHrECZI9JnR-r5lhJmhHavx-M9ulu13-pHlUygohRnpOHjYnlCLGMEGz5udn7WHatjq6NkWbhrQIVg9t2kw2jVBan3I76LyA9qxMum6_vv-4IubF3jGkqh2q213raMG1GWI1WxjqorMNMY36dVtJa51DSbE1MH0DiBVZI6nYtA52jxqTCz5UxLKeOl1KKFM9HemydvvHRVgvM9gpjdvHzQOvhwJPbvbT5sv7d1fnH7vLTx8uzt9edpZLNnVCWmOkdJQSAZRySqmQhnqYY6wREj0zgJhBknnuKed6zvhcEML53DmBgZ42FweuS3ql1jmMOm9V0kHtAykvlM5TsAMog_uee4Z7gQyzHgzHDpixnIJ3TPrKenNgrTdmBGchTlkPR9DjTAxLtUjXSnDe415WwNkNIKevGyiTGkPZFV1HSJuiCGNSytphVqXP70hXaZNrk3Yq3hNCmBBVhQ4qW2tdMvjbx2CkdpOm7k5atTz79xO3hj-jVQXdQVDq1Py99b_A38kR34c</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2456222477</pqid></control><display><type>article</type><title>Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Sage Journals GOLD Open Access 2024</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Guo, Xudong ; Wang, Hanbo ; Xiang, Yuzhu ; Jin, Xunbo ; Jiang, Shaobo</creator><creatorcontrib>Guo, Xudong ; Wang, Hanbo ; Xiang, Yuzhu ; Jin, Xunbo ; Jiang, Shaobo</creatorcontrib><description>Objective
To compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma.
Methods
We retrospectively collected data from patients who underwent HALRN or LRN for stage ≥T2b renal cell carcinoma from January 2011 to January 2018 in our institution. The patients’ demographics, perioperative parameters, and postoperative follow-up data were compared between the two groups. The survival outcome was estimated using the Kaplan–Meier method.
Results
The HALRN group comprised 78 patients, and the LRN group comprised 63 patients. The median operative duration was significantly shorter in the HALRN than LRN group. The two groups were equivalent in terms of the incision length, blood loss, complication rate, and duration of hospitalization. In the HALRN and LRN groups, the 5-year overall survival rates were 69.4% and 73.1%, the 5-year cancer-specific survival rates were 80.0% and 83.3%, and the 5-year progression-free survival rates were 66.4% and 74.7%, respectively, with no significant differences.
Conclusions
Compared with LRN, HALRN may offer a shorter operative duration and equivalent surgical outcomes without sacrificing oncological efficacy. In addition, HALRN has specific advantages for extremely large and complicated renal tumors.</description><identifier>ISSN: 0300-0605</identifier><identifier>EISSN: 1473-2300</identifier><identifier>DOI: 10.1177/0300060520961238</identifier><identifier>PMID: 33044120</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Carcinoma, Renal Cell - surgery ; Hand-Assisted Laparoscopy ; Humans ; Kidney cancer ; Kidney Neoplasms - surgery ; Laparoscopy ; Nephrectomy ; Retrospective Clinical Research Report ; Retrospective Studies ; Treatment Outcome</subject><ispartof>Journal of international medical research, 2020-10, Vol.48 (10), p.300060520961238-300060520961238</ispartof><rights>The Author(s) 2020</rights><rights>The Author(s) 2020. This work is licensed under the Creative Commons Attribution – Non-Commercial License https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2020 2020 SAGE Publications</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c594t-79cbb99d3327e33533379b3fe811a00764be04b094f5f355a8458722558dd71e3</citedby><cites>FETCH-LOGICAL-c594t-79cbb99d3327e33533379b3fe811a00764be04b094f5f355a8458722558dd71e3</cites><orcidid>0000-0002-2389-4751</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556169/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556169/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,21966,27853,27924,27925,44945,45333,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33044120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guo, Xudong</creatorcontrib><creatorcontrib>Wang, Hanbo</creatorcontrib><creatorcontrib>Xiang, Yuzhu</creatorcontrib><creatorcontrib>Jin, Xunbo</creatorcontrib><creatorcontrib>Jiang, Shaobo</creatorcontrib><title>Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy</title><title>Journal of international medical research</title><addtitle>J Int Med Res</addtitle><description>Objective
To compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma.
Methods
We retrospectively collected data from patients who underwent HALRN or LRN for stage ≥T2b renal cell carcinoma from January 2011 to January 2018 in our institution. The patients’ demographics, perioperative parameters, and postoperative follow-up data were compared between the two groups. The survival outcome was estimated using the Kaplan–Meier method.
Results
The HALRN group comprised 78 patients, and the LRN group comprised 63 patients. The median operative duration was significantly shorter in the HALRN than LRN group. The two groups were equivalent in terms of the incision length, blood loss, complication rate, and duration of hospitalization. In the HALRN and LRN groups, the 5-year overall survival rates were 69.4% and 73.1%, the 5-year cancer-specific survival rates were 80.0% and 83.3%, and the 5-year progression-free survival rates were 66.4% and 74.7%, respectively, with no significant differences.
Conclusions
Compared with LRN, HALRN may offer a shorter operative duration and equivalent surgical outcomes without sacrificing oncological efficacy. In addition, HALRN has specific advantages for extremely large and complicated renal tumors.</description><subject>Carcinoma, Renal Cell - surgery</subject><subject>Hand-Assisted Laparoscopy</subject><subject>Humans</subject><subject>Kidney cancer</subject><subject>Kidney Neoplasms - surgery</subject><subject>Laparoscopy</subject><subject>Nephrectomy</subject><subject>Retrospective Clinical Research Report</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>0300-0605</issn><issn>1473-2300</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNp1kkuOEzEQhlsIxISBPSvUEpth0eBnO2aBhEY8RhqJBcPa8qOcOOq2g90ZlCNwEM7BXTgJTjIMZCQ2tlz1_5_tqmqapxi9xFiIV4gihHrECZI9JnR-r5lhJmhHavx-M9ulu13-pHlUygohRnpOHjYnlCLGMEGz5udn7WHatjq6NkWbhrQIVg9t2kw2jVBan3I76LyA9qxMum6_vv-4IubF3jGkqh2q213raMG1GWI1WxjqorMNMY36dVtJa51DSbE1MH0DiBVZI6nYtA52jxqTCz5UxLKeOl1KKFM9HemydvvHRVgvM9gpjdvHzQOvhwJPbvbT5sv7d1fnH7vLTx8uzt9edpZLNnVCWmOkdJQSAZRySqmQhnqYY6wREj0zgJhBknnuKed6zvhcEML53DmBgZ42FweuS3ql1jmMOm9V0kHtAykvlM5TsAMog_uee4Z7gQyzHgzHDpixnIJ3TPrKenNgrTdmBGchTlkPR9DjTAxLtUjXSnDe415WwNkNIKevGyiTGkPZFV1HSJuiCGNSytphVqXP70hXaZNrk3Yq3hNCmBBVhQ4qW2tdMvjbx2CkdpOm7k5atTz79xO3hj-jVQXdQVDq1Py99b_A38kR34c</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>Guo, Xudong</creator><creator>Wang, Hanbo</creator><creator>Xiang, Yuzhu</creator><creator>Jin, Xunbo</creator><creator>Jiang, Shaobo</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>SAGE Publishing</general><scope>AFRWT</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2389-4751</orcidid></search><sort><creationdate>20201001</creationdate><title>Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy</title><author>Guo, Xudong ; Wang, Hanbo ; Xiang, Yuzhu ; Jin, Xunbo ; Jiang, Shaobo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c594t-79cbb99d3327e33533379b3fe811a00764be04b094f5f355a8458722558dd71e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Carcinoma, Renal Cell - surgery</topic><topic>Hand-Assisted Laparoscopy</topic><topic>Humans</topic><topic>Kidney cancer</topic><topic>Kidney Neoplasms - surgery</topic><topic>Laparoscopy</topic><topic>Nephrectomy</topic><topic>Retrospective Clinical Research Report</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guo, Xudong</creatorcontrib><creatorcontrib>Wang, Hanbo</creatorcontrib><creatorcontrib>Xiang, Yuzhu</creatorcontrib><creatorcontrib>Jin, Xunbo</creatorcontrib><creatorcontrib>Jiang, Shaobo</creatorcontrib><collection>Sage Journals GOLD Open Access 2024</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of international medical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guo, Xudong</au><au>Wang, Hanbo</au><au>Xiang, Yuzhu</au><au>Jin, Xunbo</au><au>Jiang, Shaobo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy</atitle><jtitle>Journal of international medical research</jtitle><addtitle>J Int Med Res</addtitle><date>2020-10-01</date><risdate>2020</risdate><volume>48</volume><issue>10</issue><spage>300060520961238</spage><epage>300060520961238</epage><pages>300060520961238-300060520961238</pages><issn>0300-0605</issn><eissn>1473-2300</eissn><abstract>Objective
To compare the operative and oncologic outcomes between hand-assisted laparoscopic radical nephrectomy (HALRN) and laparoscopic radical nephrectomy (LRN) for large (stage ≥T2b) and locally advanced renal cell carcinoma.
Methods
We retrospectively collected data from patients who underwent HALRN or LRN for stage ≥T2b renal cell carcinoma from January 2011 to January 2018 in our institution. The patients’ demographics, perioperative parameters, and postoperative follow-up data were compared between the two groups. The survival outcome was estimated using the Kaplan–Meier method.
Results
The HALRN group comprised 78 patients, and the LRN group comprised 63 patients. The median operative duration was significantly shorter in the HALRN than LRN group. The two groups were equivalent in terms of the incision length, blood loss, complication rate, and duration of hospitalization. In the HALRN and LRN groups, the 5-year overall survival rates were 69.4% and 73.1%, the 5-year cancer-specific survival rates were 80.0% and 83.3%, and the 5-year progression-free survival rates were 66.4% and 74.7%, respectively, with no significant differences.
Conclusions
Compared with LRN, HALRN may offer a shorter operative duration and equivalent surgical outcomes without sacrificing oncological efficacy. In addition, HALRN has specific advantages for extremely large and complicated renal tumors.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>33044120</pmid><doi>10.1177/0300060520961238</doi><orcidid>https://orcid.org/0000-0002-2389-4751</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-0605 |
| ispartof | Journal of international medical research, 2020-10, Vol.48 (10), p.300060520961238-300060520961238 |
| issn | 0300-0605 1473-2300 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2449994414 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Sage Journals GOLD Open Access 2024; PubMed Central; Alma/SFX Local Collection |
| subjects | Carcinoma, Renal Cell - surgery Hand-Assisted Laparoscopy Humans Kidney cancer Kidney Neoplasms - surgery Laparoscopy Nephrectomy Retrospective Clinical Research Report Retrospective Studies Treatment Outcome |
| title | Safety and oncological outcomes for large (stage ≥T2b) and locally advanced renal cell carcinoma: comparison between laparoscopic and modified hand-assisted laparoscopic radical nephrectomy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T12%3A58%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Safety%20and%20oncological%20outcomes%20for%20large%20(stage%20%E2%89%A5T2b)%20and%20locally%20advanced%20renal%20cell%20carcinoma:%20comparison%20between%20laparoscopic%20and%20modified%20hand-assisted%20laparoscopic%20radical%20nephrectomy&rft.jtitle=Journal%20of%20international%20medical%20research&rft.au=Guo,%20Xudong&rft.date=2020-10-01&rft.volume=48&rft.issue=10&rft.spage=300060520961238&rft.epage=300060520961238&rft.pages=300060520961238-300060520961238&rft.issn=0300-0605&rft.eissn=1473-2300&rft_id=info:doi/10.1177/0300060520961238&rft_dat=%3Cproquest_doaj_%3E2456222477%3C/proquest_doaj_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2456222477&rft_id=info:pmid/33044120&rft_sage_id=10.1177_0300060520961238&rft_doaj_id=oai_doaj_org_article_b1665f41670b4cfeb51de4bc53efd49f&rfr_iscdi=true |