Sclerotic bone lesions caused by non-infectious and non-neoplastic diseases: a review of the imaging and clinicopathologic findings
Bone sclerosis is a focal, multifocal, or diffuse increase in the density of the bone matrix on radiographs or computed tomography (CT) imaging. This radiological finding can be caused by a broad spectrum of diseases, such as congenital and developmental disorders, depositional disorders, and metabo...
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| Veröffentlicht in: | Skeletal radiology 2021-05, Vol.50 (5), p.847-869 |
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| creator | Gulati, Vaibhav Chalian, Majid Yi, Jaehyuck Thakur, Uma Chhabra, Avneesh |
| description | Bone sclerosis is a focal, multifocal, or diffuse increase in the density of the bone matrix on radiographs or computed tomography (CT) imaging. This radiological finding can be caused by a broad spectrum of diseases, such as congenital and developmental disorders, depositional disorders, and metabolic diseases. The differential diagnosis can be effectively narrowed by an astute radiologist in the light of the clinical picture and typical findings on imaging. Some of these lesions are rare and have been described as case reports and series in the literature. This article aims to collate the clinical-radiologic findings of non-infectious and non-neoplastic causes of bone sclerosis with relevant imaging illustrations. |
| doi_str_mv | 10.1007/s00256-020-03644-0 |
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| subjects | Antimitotic agents Antineoplastic agents Bone density Bone diseases Bone imaging Bone lesions Bone matrix Bones Case reports Computed tomography CT imaging Density Developmental disabilities Diagnosis Diagnostic imaging Differential diagnosis Disorders Dysplasia Genetic disorders Imaging Lesions Medical imaging Medicine Medicine & Public Health Metabolic disorders Nuclear Medicine Orthopedics Pathology Radiographs Radiography Radiology Review Article Sclerosis |
| title | Sclerotic bone lesions caused by non-infectious and non-neoplastic diseases: a review of the imaging and clinicopathologic findings |
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