Dendrimer-based micelles with highly potent targeting to sites of active bone turnover for the treatment of bone metastasis

[Display omitted] Bone-drug targeting therapies using nanoparticles based on targeting ligands remain challenging due to their uptake clearance at non-target sites such as the liver, kidney, and spleen. Furthermore, the distribution sites of nanoparticles in bones have not been fully investigated, t...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2020-12, Vol.157, p.85-96
Hauptverfasser:	Yamashita, Shugo, Katsumi, Hidemasa, Shimizu, Erika, Nakao, Yuto, Yoshioka, Ayane, Fukui, Minako, Kimura, Hiroyuki, Sakane, Toshiyasu, Yamamoto, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone metastasis Bone targeting Dendrimer Drug delivery
Online-Zugang:	Volltext
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