Salivary Testing for SARS-CoV-2 Detection: Will It Help the Implant Dentist?
The American Dental Association has recommended taking a recent travel history and checking respiratory symptoms and body temperature as screening tools in conjunction with the dental team wearing a plethora of personal protective equipment (PPE). The salivary glands, tongue, and lungs are considere...
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Veröffentlicht in: | The Journal of oral implantology 2020-08, Vol.46 (4), p.363-363 |
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description | The American Dental Association has recommended taking a recent travel history and checking respiratory symptoms and body temperature as screening tools in conjunction with the dental team wearing a plethora of personal protective equipment (PPE). The salivary glands, tongue, and lungs are considered possible hosts of 2019-nCoV due to expression of ACE2 receptors.1 Additionally, ACE2 receptors are concentrated on the cell surfaces of epithelial cells of the tongue and oral mucosal tissues.2 ACE2 receptors are responsible for transporting the virus from the extracellular environment to intracellular sites, which leads to infection in the patient. The Rao group concluded that saliva had a better detection rate of SARS-CoV-2 via RT-PCR assay in comparison to an NPS.4 However, Skolimowska et al.5 conducted a prospective cross-sectional study limited to acute symptomatic ( |
doi_str_mv | 10.1563/AAID-JOI-D-20-EDITORIAL.4604 |
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The salivary glands, tongue, and lungs are considered possible hosts of 2019-nCoV due to expression of ACE2 receptors.1 Additionally, ACE2 receptors are concentrated on the cell surfaces of epithelial cells of the tongue and oral mucosal tissues.2 ACE2 receptors are responsible for transporting the virus from the extracellular environment to intracellular sites, which leads to infection in the patient. The Rao group concluded that saliva had a better detection rate of SARS-CoV-2 via RT-PCR assay in comparison to an NPS.4 However, Skolimowska et al.5 conducted a prospective cross-sectional study limited to acute symptomatic (<7-day duration) healthcare workers and their household contacts who presented to a COVID-19 specific clinic in London between April 28 and May 7, 2020.</description><identifier>ISSN: 0160-6972</identifier><identifier>EISSN: 1548-1336</identifier><identifier>DOI: 10.1563/AAID-JOI-D-20-EDITORIAL.4604</identifier><identifier>PMID: 33031548</identifier><language>eng</language><publisher>United States: Allen Press Inc</publisher><subject>ACE2 ; Angiotensin-converting enzyme 2 ; Asymptomatic ; Betacoronavirus ; Body temperature ; Clinical Laboratory Techniques ; Coronavirus Infections - diagnosis ; Coronaviruses ; COVID-19 ; COVID-19 diagnostic tests ; COVID-19 Testing ; Dental care ; Dental Implants ; Dentists ; Disease transmission ; Epithelial cells ; Humans ; Medical personnel ; Mucosa ; Pandemics ; Patients ; Personal protective equipment ; Pneumonia, Viral ; Polymerase chain reaction ; RNA polymerase ; Saliva ; Saliva - virology ; Salivary gland ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome ; Severe acute respiratory syndrome coronavirus 2 ; Tongue</subject><ispartof>The Journal of oral implantology, 2020-08, Vol.46 (4), p.363-363</ispartof><rights>Copyright Allen Press Publishing Services 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c346t-92860dc7bd2bb9eddcad66d62a5ec16d68d908f5f7b68284a2eed265574e774c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33031548$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rutkowski, James L</creatorcontrib><title>Salivary Testing for SARS-CoV-2 Detection: Will It Help the Implant Dentist?</title><title>The Journal of oral implantology</title><addtitle>J Oral Implantol</addtitle><description>The American Dental Association has recommended taking a recent travel history and checking respiratory symptoms and body temperature as screening tools in conjunction with the dental team wearing a plethora of personal protective equipment (PPE). The salivary glands, tongue, and lungs are considered possible hosts of 2019-nCoV due to expression of ACE2 receptors.1 Additionally, ACE2 receptors are concentrated on the cell surfaces of epithelial cells of the tongue and oral mucosal tissues.2 ACE2 receptors are responsible for transporting the virus from the extracellular environment to intracellular sites, which leads to infection in the patient. The Rao group concluded that saliva had a better detection rate of SARS-CoV-2 via RT-PCR assay in comparison to an NPS.4 However, Skolimowska et al.5 conducted a prospective cross-sectional study limited to acute symptomatic (<7-day duration) healthcare workers and their household contacts who presented to a COVID-19 specific clinic in London between April 28 and May 7, 2020.</description><subject>ACE2</subject><subject>Angiotensin-converting enzyme 2</subject><subject>Asymptomatic</subject><subject>Betacoronavirus</subject><subject>Body temperature</subject><subject>Clinical Laboratory Techniques</subject><subject>Coronavirus Infections - diagnosis</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 diagnostic tests</subject><subject>COVID-19 Testing</subject><subject>Dental care</subject><subject>Dental Implants</subject><subject>Dentists</subject><subject>Disease transmission</subject><subject>Epithelial cells</subject><subject>Humans</subject><subject>Medical personnel</subject><subject>Mucosa</subject><subject>Pandemics</subject><subject>Patients</subject><subject>Personal protective equipment</subject><subject>Pneumonia, Viral</subject><subject>Polymerase chain reaction</subject><subject>RNA polymerase</subject><subject>Saliva</subject><subject>Saliva - 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diagnosis</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 diagnostic tests</topic><topic>COVID-19 Testing</topic><topic>Dental care</topic><topic>Dental Implants</topic><topic>Dentists</topic><topic>Disease transmission</topic><topic>Epithelial cells</topic><topic>Humans</topic><topic>Medical personnel</topic><topic>Mucosa</topic><topic>Pandemics</topic><topic>Patients</topic><topic>Personal protective equipment</topic><topic>Pneumonia, Viral</topic><topic>Polymerase chain reaction</topic><topic>RNA polymerase</topic><topic>Saliva</topic><topic>Saliva - virology</topic><topic>Salivary gland</topic><topic>SARS-CoV-2</topic><topic>Severe Acute Respiratory Syndrome</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Tongue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rutkowski, James L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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subjects | ACE2 Angiotensin-converting enzyme 2 Asymptomatic Betacoronavirus Body temperature Clinical Laboratory Techniques Coronavirus Infections - diagnosis Coronaviruses COVID-19 COVID-19 diagnostic tests COVID-19 Testing Dental care Dental Implants Dentists Disease transmission Epithelial cells Humans Medical personnel Mucosa Pandemics Patients Personal protective equipment Pneumonia, Viral Polymerase chain reaction RNA polymerase Saliva Saliva - virology Salivary gland SARS-CoV-2 Severe Acute Respiratory Syndrome Severe acute respiratory syndrome coronavirus 2 Tongue |
title | Salivary Testing for SARS-CoV-2 Detection: Will It Help the Implant Dentist? |
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