Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood
Energy balance is preserved through the exchange between body weight and adipose tissue across the multi-faceted complex network that is composed of the sensorial, metabolic, and neuro-endocrine circuits. The olfactory control of energy homeostasis is maintained through the interplay between the olf...
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Veröffentlicht in: | International journal of pediatric otorhinolaryngology 2020-12, Vol.139, p.110415-110415, Article 110415 |
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container_title | International journal of pediatric otorhinolaryngology |
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creator | Karaoglan, Murat Colakoglu Er, Hale |
description | Energy balance is preserved through the exchange between body weight and adipose tissue across the multi-faceted complex network that is composed of the sensorial, metabolic, and neuro-endocrine circuits. The olfactory control of energy homeostasis is maintained through the interplay between the olfactory bulb (OB) and adipose tissue. While extremely studied, most researches still report controversial results and sensorial regulation of obesity is not fully understood. This study aims to investigate the interplay between olfactory bulb volume (OBV) as a radiological clue of sensorial control and obesity in children.
Children (n = 195) were classified into four groups based on body mass index (BMI) percentiles: normal weight (n = 89), overweight (n = 31), obese (n = 32) and morbidly obese (n = 43). OBV were calculated using MRI.
Mean OBV was higher in children with obesity than in those of normal weights. The means of OBV are found higher in the overweight and obese children (43.76 ± 9.50–49.29 ± 8.61 mm3) than in those of morbidly obese (38.23 ± 11.52 mm3) (p |
doi_str_mv | 10.1016/j.ijporl.2020.110415 |
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Children (n = 195) were classified into four groups based on body mass index (BMI) percentiles: normal weight (n = 89), overweight (n = 31), obese (n = 32) and morbidly obese (n = 43). OBV were calculated using MRI.
Mean OBV was higher in children with obesity than in those of normal weights. The means of OBV are found higher in the overweight and obese children (43.76 ± 9.50–49.29 ± 8.61 mm3) than in those of morbidly obese (38.23 ± 11.52 mm3) (p < 0.001). In overweight and obese children, a positive correlation were found between the BMI and OBV (roverweigh = 0.275-robese = 0.377), while in the morbidly obese group, there was a negative correlation (rseverelyobese = −0.445).
This study reveals that OBV is higher in obese children. Also, it shows that there is a positive correlation between OBV and BMI in overweight and obese children and a negative correlation in the morbidly obese group. These radiological bimodal changes in OBV indicate that olfactory control acts to provide energy balance, mediated by positive in the overweight and obese children, negative feedback in the morbidly obese group.
•The olfactory control of energy homeostasis is maintained through the interplay of the olfactory bulb with adipose tissue.•Bimodal changes in olfactory bulb volume indicate that olfactory control acts to provide energy balance depend on BMI.•This study showed that the olfactory bulb volume was higher in overweight and obese but smaller in morbidly obese children</description><identifier>ISSN: 0165-5876</identifier><identifier>EISSN: 1872-8464</identifier><identifier>DOI: 10.1016/j.ijporl.2020.110415</identifier><language>eng</language><publisher>Elsevier B.V</publisher><subject>Body mass index ; Obesity ; Olfactory bulb volume</subject><ispartof>International journal of pediatric otorhinolaryngology, 2020-12, Vol.139, p.110415-110415, Article 110415</ispartof><rights>2020 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c339t-4c00ba00090e7648a7700135bc7ed94d28b38ccef317326945c937537d7a36653</citedby><cites>FETCH-LOGICAL-c339t-4c00ba00090e7648a7700135bc7ed94d28b38ccef317326945c937537d7a36653</cites><orcidid>0000-0002-5210-734X ; 0000-0002-2861-3568</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ijporl.2020.110415$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids></links><search><creatorcontrib>Karaoglan, Murat</creatorcontrib><creatorcontrib>Colakoglu Er, Hale</creatorcontrib><title>Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood</title><title>International journal of pediatric otorhinolaryngology</title><description>Energy balance is preserved through the exchange between body weight and adipose tissue across the multi-faceted complex network that is composed of the sensorial, metabolic, and neuro-endocrine circuits. The olfactory control of energy homeostasis is maintained through the interplay between the olfactory bulb (OB) and adipose tissue. While extremely studied, most researches still report controversial results and sensorial regulation of obesity is not fully understood. This study aims to investigate the interplay between olfactory bulb volume (OBV) as a radiological clue of sensorial control and obesity in children.
Children (n = 195) were classified into four groups based on body mass index (BMI) percentiles: normal weight (n = 89), overweight (n = 31), obese (n = 32) and morbidly obese (n = 43). OBV were calculated using MRI.
Mean OBV was higher in children with obesity than in those of normal weights. The means of OBV are found higher in the overweight and obese children (43.76 ± 9.50–49.29 ± 8.61 mm3) than in those of morbidly obese (38.23 ± 11.52 mm3) (p < 0.001). In overweight and obese children, a positive correlation were found between the BMI and OBV (roverweigh = 0.275-robese = 0.377), while in the morbidly obese group, there was a negative correlation (rseverelyobese = −0.445).
This study reveals that OBV is higher in obese children. Also, it shows that there is a positive correlation between OBV and BMI in overweight and obese children and a negative correlation in the morbidly obese group. These radiological bimodal changes in OBV indicate that olfactory control acts to provide energy balance, mediated by positive in the overweight and obese children, negative feedback in the morbidly obese group.
•The olfactory control of energy homeostasis is maintained through the interplay of the olfactory bulb with adipose tissue.•Bimodal changes in olfactory bulb volume indicate that olfactory control acts to provide energy balance depend on BMI.•This study showed that the olfactory bulb volume was higher in overweight and obese but smaller in morbidly obese children</description><subject>Body mass index</subject><subject>Obesity</subject><subject>Olfactory bulb volume</subject><issn>0165-5876</issn><issn>1872-8464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMouK7-Aw85eumaNEnTXgRZ_IIFQfQc0mS6zZpt1qRd3H9vl-rV08DwPi8zD0LXlCwoocXtZuE2uxD9Iif5uKKEU3GCZrSUeVbygp-i2RgTmShlcY4uUtoQQiURYoY-37R1wYe1M9pj2DsLnQHcB2xa3a0hYdfhvgUcfKNNH-IB14Ov8T74YQvYwg4667o1Dh2ugz3grU5HxsL3H2la520bgr1EZ432Ca5-5xx9PD68L5-z1evTy_J-lRnGqj7jhpBaE0IqArLgpZZyPJeJ2kiwFbd5WbPSGGgYlSwvKi5MxaRg0krNikKwObqZencxfA2QerV1yYD3uoMwJJVzXlVC8JyMUT5FTQwpRWjULrqtjgdFiTq6VRs1uVVHt2pyO2J3EwbjG3sHUSXjjuKsi2B6ZYP7v-AHhECESQ</recordid><startdate>202012</startdate><enddate>202012</enddate><creator>Karaoglan, Murat</creator><creator>Colakoglu Er, Hale</creator><general>Elsevier B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5210-734X</orcidid><orcidid>https://orcid.org/0000-0002-2861-3568</orcidid></search><sort><creationdate>202012</creationdate><title>Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood</title><author>Karaoglan, Murat ; Colakoglu Er, Hale</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-4c00ba00090e7648a7700135bc7ed94d28b38ccef317326945c937537d7a36653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Body mass index</topic><topic>Obesity</topic><topic>Olfactory bulb volume</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karaoglan, Murat</creatorcontrib><creatorcontrib>Colakoglu Er, Hale</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of pediatric otorhinolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karaoglan, Murat</au><au>Colakoglu Er, Hale</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood</atitle><jtitle>International journal of pediatric otorhinolaryngology</jtitle><date>2020-12</date><risdate>2020</risdate><volume>139</volume><spage>110415</spage><epage>110415</epage><pages>110415-110415</pages><artnum>110415</artnum><issn>0165-5876</issn><eissn>1872-8464</eissn><abstract>Energy balance is preserved through the exchange between body weight and adipose tissue across the multi-faceted complex network that is composed of the sensorial, metabolic, and neuro-endocrine circuits. The olfactory control of energy homeostasis is maintained through the interplay between the olfactory bulb (OB) and adipose tissue. While extremely studied, most researches still report controversial results and sensorial regulation of obesity is not fully understood. This study aims to investigate the interplay between olfactory bulb volume (OBV) as a radiological clue of sensorial control and obesity in children.
Children (n = 195) were classified into four groups based on body mass index (BMI) percentiles: normal weight (n = 89), overweight (n = 31), obese (n = 32) and morbidly obese (n = 43). OBV were calculated using MRI.
Mean OBV was higher in children with obesity than in those of normal weights. The means of OBV are found higher in the overweight and obese children (43.76 ± 9.50–49.29 ± 8.61 mm3) than in those of morbidly obese (38.23 ± 11.52 mm3) (p < 0.001). In overweight and obese children, a positive correlation were found between the BMI and OBV (roverweigh = 0.275-robese = 0.377), while in the morbidly obese group, there was a negative correlation (rseverelyobese = −0.445).
This study reveals that OBV is higher in obese children. Also, it shows that there is a positive correlation between OBV and BMI in overweight and obese children and a negative correlation in the morbidly obese group. These radiological bimodal changes in OBV indicate that olfactory control acts to provide energy balance, mediated by positive in the overweight and obese children, negative feedback in the morbidly obese group.
•The olfactory control of energy homeostasis is maintained through the interplay of the olfactory bulb with adipose tissue.•Bimodal changes in olfactory bulb volume indicate that olfactory control acts to provide energy balance depend on BMI.•This study showed that the olfactory bulb volume was higher in overweight and obese but smaller in morbidly obese children</abstract><pub>Elsevier B.V</pub><doi>10.1016/j.ijporl.2020.110415</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-5210-734X</orcidid><orcidid>https://orcid.org/0000-0002-2861-3568</orcidid></addata></record> |
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subjects | Body mass index Obesity Olfactory bulb volume |
title | Radiological evidence to changes in the olfactory bulb volume depending on body mass index in the childhood |
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