Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism

The mechanism and function of autophagy as a highly-conserved bulk degradation pathway are well studied, but the physiological role of autophagy remains poorly understood. We show that autophagy is involved in the adaptation of Saccharomyces cerevisiae to respiratory growth through its recycling of...

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Veröffentlicht in:	Nature communications 2020-10, Vol.11 (1), p.5052-5052, Article 5052
Hauptverfasser:	May, Alexander I., Prescott, Mark, Ohsumi, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	13 631/80/39 631/80/642/333 631/80/83 64 Adaptation Adaptation, Physiological Autophagy Autophagy - physiology Carbon Carbon - metabolism Cell Respiration - physiology Glycolysis Humanities and Social Sciences Metabolism Metabolites Mitochondria Mitochondria - metabolism Mitochondrial Proteins - biosynthesis multidisciplinary Phagocytosis Protein biosynthesis Protein Biosynthesis - physiology Protein expression Protein synthesis Protein turnover Proteins RNA, Transfer - metabolism Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - physiology Saccharomyces cerevisiae Proteins - metabolism Science Science (multidisciplinary) Serine Serine - metabolism Supplements tRNA tRNA Ala Yeast Yeasts
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