Analysis of metabolomics profile in hypothyroid patients before and after thyroid hormone replacement

Purpose The serum metabolic changes occurring during the transition from hypothyroidism to euthyroidism are not known. This study aimed to determine the metabolomic profile in hypothyroid patients before (HypoT 0 ) and after (HypoT 1 ) euthyroidism achieved through levothyroxine (L-T4) treatment. Me...

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Veröffentlicht in:	Journal of endocrinological investigation 2021-06, Vol.44 (6), p.1309-1319
Hauptverfasser:	Piras, C., Pibiri, M., Leoni, V. P., Balsamo, A., Tronci, L., Arisci, N., Mariotti, S., Atzori, L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Citric acid Creatinine Discriminant analysis Drug therapy Endocrinology Glycerol Hypothyroidism Inositol Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Metabolism Metabolomics NMR Nuclear magnetic resonance Original Article Proline Serine Serum levels Spectroscopy Taurine Thyroid gland Thyroid hormones Thyroid-stimulating hormone Thyroxine Triiodothyronine
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