UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections

•Recipients of UM171-expanded cord blood show robust T cell reconstitution.•Recipients of UM171 grafts show high T cell receptor repertoire diversity post-transplant.•UM171 expansion increases the frequency and potency of common lymphoid progenitors.•UM171 grafts are associated with low rate of seve...

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Veröffentlicht in:	Transplantation and cellular therapy 2021-01, Vol.27 (1), p.76.e1-76.e9
Hauptverfasser:	Dumont-Lagacé, Maude, Li, Qi, Tanguay, Mégane, Chagraoui, Jalila, Kientega, Tibila, Cardin, Guillaume B., Brasey, Ann, Trofimov, Assya, Carli, Cédric, Ahmad, Imran, Bambace, Nadia M., Bernard, Léa, Kiss, Thomas L., Roy, Jean, Roy, Denis-Claude, Lemieux, Sébastien, Perreault, Claude, Rodier, Francis, Dufresne, Simon Frédéric, Busque, Lambert, Lachance, Silvy, Sauvageau, Guy, Cohen, Sandra, Delisle, Jean-Sébastien
Format:	Artikel
Sprache:	eng
Schlagworte:	Hematopoietic stem cell transplantation Infections T cell reconstitution TCR repertoire diversity TCR sequencing UM171-expanded cord blood
Online-Zugang:	Volltext
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