5-aminolevulinic acid photodynamic therapy inhibits invasion and metastasis of SCL-1 cells probably via MTSS1 and p63 gene related pathways

•ALA-PDT inhibits the migration and invasion abilities of SCL-1 cells in vitro.•Both the mRNA and protein expression levels were up-regulated in MTSS1 gene and down-regulated in p63 gene after ALA-PDT treatment.•This study provides potential targets for the therapy of cutaneous squamous cell carcino...

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Veröffentlicht in:	Photodiagnosis and photodynamic therapy 2020-12, Vol.32, p.102039-102039, Article 102039
Hauptverfasser:	Ye, TingLu, Chen, TingTing, Jiang, Bin, Yang, LiLi, Liu, XiaoMing, Chen, BanCheng, Zou, YanFen, Yu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	5-aminolevulinic acid Aminolevulinic Acid - pharmacology Aminolevulinic Acid - therapeutic use Carcinoma, Squamous Cell - drug therapy Cell Line, Tumor Humans Invasion Membrane Proteins Metastasis Microfilament Proteins - therapeutic use Neoplasm Proteins - therapeutic use Nonmelanoma skin cancer Photochemotherapy - methods Photodynamic therapy Photosensitizing Agents - pharmacology Photosensitizing Agents - therapeutic use Skin Neoplasms - drug therapy Skin Neoplasms - genetics Squamous cell carcinoma
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