Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3a

This study investigated if the nephroprotective effect of Curcumin in streptozotocin-induced type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p66Shc and examined the underlying mechanisms. Rats were divided into 4 groups (n = 12/group) as control, control + Curcumin (100 m...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2021-01, Vol.87, p.108515-108515, Article 108515
Hauptverfasser:	ALTamimi, Jozaa Z., AlFaris, Nora A., AL-Farga, Ammar M., Alshammari, Ghedeir M., BinMowyna, Mona N., Yahya, Mohammed A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Curcumin Diabetes mellitus FOXO-3a Nephropathy p66Shc
Online-Zugang:	Volltext
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