Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE-/- mice fed with HFD

Dingxin Recipe (DXR) is a traditional Chinese medicine formula that has been reported to be effective and safe treatment for cardiovascular diseases, such as arrhythmias, coronary heart disease. Dingxin Recipe IV (DXR IV) was further improved from the DXR according to the traditional use. However, t...

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Veröffentlicht in:	Journal of ethnopharmacology 2021-02, Vol.266, p.113436-113436, Article 113436
Hauptverfasser:	Zhang, Yaxin, Gu, Yuyan, Chen, Yihao, Huang, Zhiyong, Li, Mei, Jiang, Weihao, Chen, Jiahui, Rao, Wenting, Luo, Shangfei, Chen, Yuyao, Chen, Junqi, Li, Lijun, Jia, Yuhua, Liu, Menghua, Zhou, Fenghua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - genetics Atherosclerosis Atherosclerosis - prevention & control Diet, High-Fat Dingxin recipe IV Drugs, Chinese Herbal - pharmacology Gastrointestinal Microbiome - drug effects Gut microbiota Lipid metabolism Lipid Metabolism - drug effects Liver X Receptors - metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Plaque, Atherosclerotic - prevention & control Sterol Regulatory Element Binding Protein 1 - metabolism Traditional Chinese medicine
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