Cardiolipin in Immune Signaling and Cell Death

Cardiolipin (CL) is a tetra-acylated diphosphatidylglycerol lipid. In physiological conditions, CL presents unsaturated chains and is located in the inner mitochondria membrane (IMM). Dead signals, infection, or disease may change the level of CL saturation and oxidation and cause its translocation...

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Veröffentlicht in:	Trends in cell biology 2020-11, Vol.30 (11), p.892-903
Hauptverfasser:	Pizzuto, Malvina, Pelegrin, Pablo
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cardiolipin Cell death Chains Diphosphatidylglycerol Immune system Inflammation Inflammatory response Leucine Lipids Membranes Mitochondria Nucleotides Oxidation Phospholipids Proteins Pyrin protein Reviews Saturation TLR4 protein Toll-like receptors Translocation
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