Mitochondrial calcium handling and heart disease in diabetes mellitus

Diabetes mellitus-induced heart disease, including diabetic cardiomyopathy, is an important medical problem and is difficult to treat. Diabetes mellitus increases the risk for heart failure and decreases cardiac myocyte function, which are linked to changes in cardiac mitochondrial energy metabolism...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2021-01, Vol.1867 (1), p.165984-165984, Article 165984
Hauptverfasser:	Diaz-Juarez, Julieta, Suarez, Jorge A., Dillmann, Wolfgang H., Suarez, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Channels - metabolism Calcium Signaling Cardiac myocytes Diabetic Cardiomyopathies - metabolism Diabetic Cardiomyopathies - pathology Diabetic cardiomyopathy Humans Mitochondria, Heart - metabolism Mitochondria, Heart - pathology Mitochondrial calcium Mitochondrial calcium uptake and release Myocytes, Cardiac - metabolism Myocytes, Cardiac - pathology Therapeutic target
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