Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes
Background To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system. Methods Thirty‐one patients who had undergone ra...
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Veröffentlicht in: | Journal of cardiovascular electrophysiology 2020-12, Vol.31 (12), p.3251-3261 |
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creator | Kose, Sedat Vurgun, Veysel K. Gokoglan, Yalcin Balli, Mehmet Kabul, Hasan K. |
description | Background
To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system.
Methods
Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes ( |
doi_str_mv | 10.1111/jce.14765 |
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fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2448411755</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2448411755</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</originalsourceid><addsrcrecordid>eNp10c9uFSEUBnBiNLZWF76AIXGjSaeFAYbp0ty0_kkTN7qeMGcOvdwwAwKj3mfxZUt7WxcmsoFwfvlyko-Q15yd8XrOd4BnXOpOPSHHXEnW9LzTT-ubSdWIXosj8iLnHWNcdEw9J0dCMM6YVsfkz8a7xYHxpxQ9QkkBTJpcuEkmbh1Qs0yPg7jdZxd8uLnjFLYmGSiYXC4O8um9BFO2WP-oGb0pLiw0YV59yTRY6tEWusZYxxljqRkx4WzKmpD-xKUkB6s3iUKYo8ffmF-SZ9b4jK8e7hPy_ery2-ZTc_314-fNh-sGhBKqAew0tL3GyfajnWyrJz6ORl2IXnaGIVpphRYgOSolW2b1BPICQHWtMFxP4oS8O-TGFH6smMswuwzovVkwrHlopewl51qpSt_-Q3dhTUvdrirN-k52vK_q_UFBCjkntENMbjZpP3A23DU21MaG-8aqffOQuI4zTn_lY0UVnB_AL-dx__-k4cvm8hB5Cw1VpDo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2470864618</pqid></control><display><type>article</type><title>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</title><source>Wiley Online Library All Journals</source><creator>Kose, Sedat ; Vurgun, Veysel K. ; Gokoglan, Yalcin ; Balli, Mehmet ; Kabul, Hasan K.</creator><creatorcontrib>Kose, Sedat ; Vurgun, Veysel K. ; Gokoglan, Yalcin ; Balli, Mehmet ; Kabul, Hasan K.</creatorcontrib><description>Background
To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system.
Methods
Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (<110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping.
Results
The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months.
Conclusions
LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</description><identifier>ISSN: 1045-3873</identifier><identifier>EISSN: 1540-8167</identifier><identifier>DOI: 10.1111/jce.14765</identifier><identifier>PMID: 33010075</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Ablation ; Catheters ; fascicular potential ; Heart ; left fascicular system ; left upper septal ; Mapping ; Morphology ; premature ventricular complex ; Radiofrequency ablation ; radiofrequency catheter ablation ; Septum ; Ventricle</subject><ispartof>Journal of cardiovascular electrophysiology, 2020-12, Vol.31 (12), p.3251-3261</ispartof><rights>2020 Wiley Periodicals LLC</rights><rights>2020 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</citedby><cites>FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</cites><orcidid>0000-0001-8624-2809</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjce.14765$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjce.14765$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33010075$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kose, Sedat</creatorcontrib><creatorcontrib>Vurgun, Veysel K.</creatorcontrib><creatorcontrib>Gokoglan, Yalcin</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Kabul, Hasan K.</creatorcontrib><title>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</title><title>Journal of cardiovascular electrophysiology</title><addtitle>J Cardiovasc Electrophysiol</addtitle><description>Background
To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system.
Methods
Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (<110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping.
Results
The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months.
Conclusions
LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</description><subject>Ablation</subject><subject>Catheters</subject><subject>fascicular potential</subject><subject>Heart</subject><subject>left fascicular system</subject><subject>left upper septal</subject><subject>Mapping</subject><subject>Morphology</subject><subject>premature ventricular complex</subject><subject>Radiofrequency ablation</subject><subject>radiofrequency catheter ablation</subject><subject>Septum</subject><subject>Ventricle</subject><issn>1045-3873</issn><issn>1540-8167</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp10c9uFSEUBnBiNLZWF76AIXGjSaeFAYbp0ty0_kkTN7qeMGcOvdwwAwKj3mfxZUt7WxcmsoFwfvlyko-Q15yd8XrOd4BnXOpOPSHHXEnW9LzTT-ubSdWIXosj8iLnHWNcdEw9J0dCMM6YVsfkz8a7xYHxpxQ9QkkBTJpcuEkmbh1Qs0yPg7jdZxd8uLnjFLYmGSiYXC4O8um9BFO2WP-oGb0pLiw0YV59yTRY6tEWusZYxxljqRkx4WzKmpD-xKUkB6s3iUKYo8ffmF-SZ9b4jK8e7hPy_ery2-ZTc_314-fNh-sGhBKqAew0tL3GyfajnWyrJz6ORl2IXnaGIVpphRYgOSolW2b1BPICQHWtMFxP4oS8O-TGFH6smMswuwzovVkwrHlopewl51qpSt_-Q3dhTUvdrirN-k52vK_q_UFBCjkntENMbjZpP3A23DU21MaG-8aqffOQuI4zTn_lY0UVnB_AL-dx__-k4cvm8hB5Cw1VpDo</recordid><startdate>202012</startdate><enddate>202012</enddate><creator>Kose, Sedat</creator><creator>Vurgun, Veysel K.</creator><creator>Gokoglan, Yalcin</creator><creator>Balli, Mehmet</creator><creator>Kabul, Hasan K.</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8624-2809</orcidid></search><sort><creationdate>202012</creationdate><title>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</title><author>Kose, Sedat ; Vurgun, Veysel K. ; Gokoglan, Yalcin ; Balli, Mehmet ; Kabul, Hasan K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Ablation</topic><topic>Catheters</topic><topic>fascicular potential</topic><topic>Heart</topic><topic>left fascicular system</topic><topic>left upper septal</topic><topic>Mapping</topic><topic>Morphology</topic><topic>premature ventricular complex</topic><topic>Radiofrequency ablation</topic><topic>radiofrequency catheter ablation</topic><topic>Septum</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kose, Sedat</creatorcontrib><creatorcontrib>Vurgun, Veysel K.</creatorcontrib><creatorcontrib>Gokoglan, Yalcin</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Kabul, Hasan K.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiovascular electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kose, Sedat</au><au>Vurgun, Veysel K.</au><au>Gokoglan, Yalcin</au><au>Balli, Mehmet</au><au>Kabul, Hasan K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</atitle><jtitle>Journal of cardiovascular electrophysiology</jtitle><addtitle>J Cardiovasc Electrophysiol</addtitle><date>2020-12</date><risdate>2020</risdate><volume>31</volume><issue>12</issue><spage>3251</spage><epage>3261</epage><pages>3251-3261</pages><issn>1045-3873</issn><eissn>1540-8167</eissn><abstract>Background
To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system.
Methods
Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (<110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping.
Results
The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months.
Conclusions
LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33010075</pmid><doi>10.1111/jce.14765</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-8624-2809</orcidid></addata></record> |
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subjects | Ablation Catheters fascicular potential Heart left fascicular system left upper septal Mapping Morphology premature ventricular complex Radiofrequency ablation radiofrequency catheter ablation Septum Ventricle |
title | Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes |
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