Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes

Background To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system. Methods Thirty‐one patients who had undergone ra...

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Veröffentlicht in:Journal of cardiovascular electrophysiology 2020-12, Vol.31 (12), p.3251-3261
Hauptverfasser: Kose, Sedat, Vurgun, Veysel K., Gokoglan, Yalcin, Balli, Mehmet, Kabul, Hasan K.
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container_issue 12
container_start_page 3251
container_title Journal of cardiovascular electrophysiology
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creator Kose, Sedat
Vurgun, Veysel K.
Gokoglan, Yalcin
Balli, Mehmet
Kabul, Hasan K.
description Background To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system. Methods Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (
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Methods Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (&lt;110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping. Results The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months. Conclusions LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</description><identifier>ISSN: 1045-3873</identifier><identifier>EISSN: 1540-8167</identifier><identifier>DOI: 10.1111/jce.14765</identifier><identifier>PMID: 33010075</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Ablation ; Catheters ; fascicular potential ; Heart ; left fascicular system ; left upper septal ; Mapping ; Morphology ; premature ventricular complex ; Radiofrequency ablation ; radiofrequency catheter ablation ; Septum ; Ventricle</subject><ispartof>Journal of cardiovascular electrophysiology, 2020-12, Vol.31 (12), p.3251-3261</ispartof><rights>2020 Wiley Periodicals LLC</rights><rights>2020 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</citedby><cites>FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</cites><orcidid>0000-0001-8624-2809</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjce.14765$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjce.14765$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33010075$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kose, Sedat</creatorcontrib><creatorcontrib>Vurgun, Veysel K.</creatorcontrib><creatorcontrib>Gokoglan, Yalcin</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Kabul, Hasan K.</creatorcontrib><title>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</title><title>Journal of cardiovascular electrophysiology</title><addtitle>J Cardiovasc Electrophysiol</addtitle><description>Background To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system. Methods Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (&lt;110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping. Results The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months. Conclusions LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</description><subject>Ablation</subject><subject>Catheters</subject><subject>fascicular potential</subject><subject>Heart</subject><subject>left fascicular system</subject><subject>left upper septal</subject><subject>Mapping</subject><subject>Morphology</subject><subject>premature ventricular complex</subject><subject>Radiofrequency ablation</subject><subject>radiofrequency catheter ablation</subject><subject>Septum</subject><subject>Ventricle</subject><issn>1045-3873</issn><issn>1540-8167</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp10c9uFSEUBnBiNLZWF76AIXGjSaeFAYbp0ty0_kkTN7qeMGcOvdwwAwKj3mfxZUt7WxcmsoFwfvlyko-Q15yd8XrOd4BnXOpOPSHHXEnW9LzTT-ubSdWIXosj8iLnHWNcdEw9J0dCMM6YVsfkz8a7xYHxpxQ9QkkBTJpcuEkmbh1Qs0yPg7jdZxd8uLnjFLYmGSiYXC4O8um9BFO2WP-oGb0pLiw0YV59yTRY6tEWusZYxxljqRkx4WzKmpD-xKUkB6s3iUKYo8ffmF-SZ9b4jK8e7hPy_ery2-ZTc_314-fNh-sGhBKqAew0tL3GyfajnWyrJz6ORl2IXnaGIVpphRYgOSolW2b1BPICQHWtMFxP4oS8O-TGFH6smMswuwzovVkwrHlopewl51qpSt_-Q3dhTUvdrirN-k52vK_q_UFBCjkntENMbjZpP3A23DU21MaG-8aqffOQuI4zTn_lY0UVnB_AL-dx__-k4cvm8hB5Cw1VpDo</recordid><startdate>202012</startdate><enddate>202012</enddate><creator>Kose, Sedat</creator><creator>Vurgun, Veysel K.</creator><creator>Gokoglan, Yalcin</creator><creator>Balli, Mehmet</creator><creator>Kabul, Hasan K.</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8624-2809</orcidid></search><sort><creationdate>202012</creationdate><title>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</title><author>Kose, Sedat ; Vurgun, Veysel K. ; Gokoglan, Yalcin ; Balli, Mehmet ; Kabul, Hasan K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3535-ce67c287edf8bfdf27d1bba593846a0eef4f373c41e55420f7dc49cc5623a17d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Ablation</topic><topic>Catheters</topic><topic>fascicular potential</topic><topic>Heart</topic><topic>left fascicular system</topic><topic>left upper septal</topic><topic>Mapping</topic><topic>Morphology</topic><topic>premature ventricular complex</topic><topic>Radiofrequency ablation</topic><topic>radiofrequency catheter ablation</topic><topic>Septum</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kose, Sedat</creatorcontrib><creatorcontrib>Vurgun, Veysel K.</creatorcontrib><creatorcontrib>Gokoglan, Yalcin</creatorcontrib><creatorcontrib>Balli, Mehmet</creatorcontrib><creatorcontrib>Kabul, Hasan K.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiovascular electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kose, Sedat</au><au>Vurgun, Veysel K.</au><au>Gokoglan, Yalcin</au><au>Balli, Mehmet</au><au>Kabul, Hasan K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes</atitle><jtitle>Journal of cardiovascular electrophysiology</jtitle><addtitle>J Cardiovasc Electrophysiol</addtitle><date>2020-12</date><risdate>2020</risdate><volume>31</volume><issue>12</issue><spage>3251</spage><epage>3261</epage><pages>3251-3261</pages><issn>1045-3873</issn><eissn>1540-8167</eissn><abstract>Background To investigate the clinical, electrocardiographic and electrophysiological characteristics, and results of catheter ablation of left upper septal (LUS) premature ventricular complexes (PVCs) arising from the proximal left fascicular system. Methods Thirty‐one patients who had undergone radiofrequency catheter ablation (RFCA) for idiopathic PVCs were enrolled in the study. All PVCs presented with narrow QRS complexes (&lt;110 ms) with precordial QRS morphology of incomplete right bundle branch block type or identical to the sinus rhythm (SR) QRS morphology. RFCA was applied to the LUS area where the earliest fascicular potential (FP) was recorded during mapping. Results The mean QRS duration during SR and PVCs were 92.3 ± 7.9 and 103.2 ± 7.3 ms, respectively. The mean fascicular potential‐ventricular interval during PVC at the target site was 32.7 ± 2.7 ms. The mean His‐ventricular (H‐V) interval during SR and PVCs were 45.1 ± 2.7 and 21.3 ± 3.6 ms, respectively. Left anterior hemiblock/left posterior hemiblock and left bundle branch block (LBBB) were observed in 16 (53.3%) and 4 (12.9%) patients after RFCA, respectively. The His to FP interval in SR and H‐V interval during PVC were found as significant markers for predicting the postablation LBBB. RFCA was acutely successful in 29 of 31 patients (93.5%) in the first procedure. Two patients had a recurrence of PVCs during follow‐up and one of them underwent a second successful ablation. The overall success rate was 90.3% (28/31) in a mean follow‐up duration of 24.3 ± 15.4 months. Conclusions LUS‐PVCs have distinctive electrocardiographic and electrophysiologic characteristics and can be managed successfully by focal RFCA with detailed FP mapping of the left upper septum with a mild risk of left bundle branch injury.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33010075</pmid><doi>10.1111/jce.14765</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-8624-2809</orcidid></addata></record>
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subjects Ablation
Catheters
fascicular potential
Heart
left fascicular system
left upper septal
Mapping
Morphology
premature ventricular complex
Radiofrequency ablation
radiofrequency catheter ablation
Septum
Ventricle
title Clinical, electrocardiographic and electrophysiological characteristics, and catheter ablation results of left upper septal premature ventricular complexes
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