HIF-1α expression in liver metastasis but not primary colorectal cancer is associated with prognosis of patients with colorectal liver metastasis

The role of hypoxia-inducible factor-1α (HIF-1α) in primary colorectal cancer (CRC) and colorectal liver metastasis (CRLM) has remained unclear. The aim of this study was to investigate HIF-1α expression and its association with prognosis in patients with CRLM with a focus on hepatic stellate cells...

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Veröffentlicht in:	World journal of surgical oncology 2020-09, Vol.18 (1), p.241-241, Article 241
Hauptverfasser:	Wada, Yuma, Morine, Yuji, Imura, Satoru, Ikemoto, Tetsuya, Saito, Yu, Takasu, Chie, Yamada, Shinichiro, Shimada, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Cell culture Cell migration Colon Colon cancer Colonic Neoplasms Colorectal cancer Colorectal carcinoma Colorectal liver metastasis Colorectal Neoplasms Fibroblasts Gene expression Growth factors Hepatectomy HIF-1α Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Hypoxia-inducible factor 1a Liver Liver cancer Liver Neoplasms Medical prognosis Metastases Metastasis Molecular biology mRNA Patients Phenotypes Prognosis Prognostic factor Stellate cells Tumor cells Tumors
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