Head and neck cancer patient-derived xenograft models – A systematic review

[Display omitted] •This is the first systematic review that summarizes the use of HNC-PDX.•In general, the studies were flawed in terms of detailing the procedures used.•PDX recapitulates the histology and molecular aspects of the original HNC tumor.•PDX represents a valuable method in translational...

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Veröffentlicht in:	Critical reviews in oncology/hematology 2020-11, Vol.155, p.103087-103087, Article 103087
Hauptverfasser:	Schuch, Lauren F., Silveira, Felipe M., Wagner, Vivian P., Borgato, Gabriell B., Rocha, Guilherme Z., Castilho, Rogerio M., Vargas, Pablo A., Martins, Manoela D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Head and neck neoplasms Preclinical drug evaluation Translational medical research Xenograft model antitumor assays
Online-Zugang:	Volltext
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