SARS-CoV-2: From Structure to Pathology, Host Immune Response and Therapeutic Management

Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the COVID-19 pandemic, has 80% sequence homology with SARS-CoV-1 and 96–98% homology with coronaviruses isolated from bats. The...

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Veröffentlicht in:	Microorganisms (Basel) 2020-09, Vol.8 (10), p.1468
Hauptverfasser:	Mihaescu, Grigore, Chifiriuc, Mariana Carmen, Iliescu, Ciprian, Vrancianu, Corneliu Ovidiu, Ditu, Lia-Mara, Marutescu, Luminita Gabriela, Grigore, Raluca, Berteșteanu, Șerban, Constantin, Marian, Gradisteanu Pircalabioru, Gratiela
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Amino acids Autoimmune diseases Coronaviridae Coronaviruses COVID-19 Diabetes mellitus Disease management Disease transmission Domestic animals Enzymes Genetic variability Genomes Glycoproteins Homology Humidity Immune response Immune system Infections Infectious diseases inflammation Ligands Metabolic disorders Metabolic syndrome Middle East respiratory syndrome Molecular modelling Multiplication Pandemics Pathology Pharmacology Physical factors Public health Respiratory diseases Review Risk analysis Risk factors RNA viruses SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Vaccine development Viral diseases Viral infections Viruses
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