Reduced H3K27me3 levels in diffuse gliomas: association with 1p/19q codeletion and difference from H3K27me3 loss in malignant peripheral nerve sheath tumors

Trimethylation of histone H3 at lysine 27 (H3K27me3) acts as a transcriptional repressor of target genes. Recent immunohistochemical studies have reported a loss of H3K27me3 modification in diffuse (especially 1p/19q-codeleted) gliomas. However, we did not observe H3K27me3 loss in diffuse gliomas us...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain tumor pathology 2021, Vol.38 (1), p.23-29
Hauptverfasser:	Kitahama, Keiichiro, Iijima, Shohei, Sumiishi, Ayumi, Hayashi, Akimasa, Nagahama, Kiyotaka, Saito, Kuniaki, Sasaki, Nobuyoshi, Kobayashi, Keiichi, Shimizu, Saki, Nagane, Motoo, Shibahara, Junji
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Brain cancer Cancer Research Cloning Epigenetics Females Glioma Medicine Medicine & Public Health Mutation Nervous system Neurology Neurosurgery Oncology Original Article Pathology Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!