Dose-escalated intensity modulated radiation therapy in patients with locally-advanced vulvar cancer - does it increase response rate?

GOG 205 safely increased clinical (cCR) and pathologic complete response (pCR) in locally-advanced vulvar cancer through dose escalation using three-dimensional radiotherapy (RT). The aim of this study is to assess the response of dose-escalated intensity modulated radiotherapy (IMRT) in locally-adv...

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Veröffentlicht in:	Gynecologic oncology 2020-12, Vol.159 (3), p.657-662
Hauptverfasser:	Richman, Adam H., Vargo, John A., Ling, Diane C., Sukumvanich, Paniti, Berger, Jessica L., Boisen, Michelle M., Edwards, Robert, Taylor, Sarah E., Courtney-Brooks, Madeleine B., Olawaiye, Alexander, Orr, Brian C., Beriwal, Sushil
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Disease-Free Survival Dose-escalated Dose-Response Relationship, Radiation Female Groin recurrence Humans IMRT Middle Aged Neoadjuvant Therapy - methods PCR Radiation Radiation Injuries - diagnosis Radiation Injuries - epidemiology Radiation Injuries - etiology Radiotherapy Dosage Radiotherapy, Intensity-Modulated - adverse effects Radiotherapy, Intensity-Modulated - methods Retrospective Studies Severity of Illness Index Vulva - pathology Vulva - radiation effects Vulva - surgery Vulvar cancer Vulvar Neoplasms - mortality Vulvar Neoplasms - pathology Vulvar Neoplasms - therapy Vulvectomy
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