Pediatric patients with orofacial granulomatosis likely to subsequently develop intestinal Crohn's disease: Brief Report

Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition presenting as perioral inflammation in the absence of systemic disease. There is continued debate regarding whether OFG is a distinct clinical disorder or a manifestation of orofacial Crohn's disease. Our retrospectiv...

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Veröffentlicht in:	Pediatric dermatology 2020-11, Vol.37 (6), p.1162-1164
Hauptverfasser:	Chen, Kristen L., Diiorio, Daren A., Chiu, Yvonne E., Sokumbi, Olayemi
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Crohn Disease - complications Crohn Disease - diagnosis Crohn's disease Dermatology Gastroenterology Granulomatosis Granulomatosis, Orofacial - diagnosis Granulomatosis, Orofacial - drug therapy Granulomatosis, Orofacial - etiology Humans Inflammation Intestine orofacial granulomatosis Patients Pediatrics Retrospective Studies Tertiary Care Centers
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container_title	Pediatric dermatology
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creator	Chen, Kristen L. Diiorio, Daren A. Chiu, Yvonne E. Sokumbi, Olayemi
description	Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition presenting as perioral inflammation in the absence of systemic disease. There is continued debate regarding whether OFG is a distinct clinical disorder or a manifestation of orofacial Crohn's disease. Our retrospective review identified 7 patients diagnosed with OFG between 2000 and 2018 at a tertiary pediatric hospital. Four of the 7 patients subsequently developed Crohn's disease with a median delay of 3.1 years (range 0.4‐6.9 years). This indicates that gastroenterology evaluation with long‐term monitoring for intestinal Crohn's disease is warranted.
doi_str_mv	10.1111/pde.14390
format	Article
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This indicates that gastroenterology evaluation with long‐term monitoring for intestinal Crohn's disease is warranted.</description><identifier>ISSN: 0736-8046</identifier><identifier>EISSN: 1525-1470</identifier><identifier>DOI: 10.1111/pde.14390</identifier><identifier>PMID: 32985729</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Child ; Crohn Disease - complications ; Crohn Disease - diagnosis ; Crohn's disease ; Dermatology ; Gastroenterology ; Granulomatosis ; Granulomatosis, Orofacial - diagnosis ; Granulomatosis, Orofacial - drug therapy ; Granulomatosis, Orofacial - etiology ; Humans ; Inflammation ; Intestine ; orofacial granulomatosis ; Patients ; Pediatrics ; Retrospective Studies ; Tertiary Care Centers</subject><ispartof>Pediatric dermatology, 2020-11, Vol.37 (6), p.1162-1164</ispartof><rights>2020 Wiley Periodicals LLC.</rights><rights>Copyright © 2020 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3530-3f288183582a5478291b29557fbb7f15d5f4f7633aa9610c445be6e673a3462e3</citedby><cites>FETCH-LOGICAL-c3530-3f288183582a5478291b29557fbb7f15d5f4f7633aa9610c445be6e673a3462e3</cites><orcidid>0000-0002-0361-9234 ; 0000-0003-2869-2718</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpde.14390$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpde.14390$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32985729$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Kristen L.</creatorcontrib><creatorcontrib>Diiorio, Daren A.</creatorcontrib><creatorcontrib>Chiu, Yvonne E.</creatorcontrib><creatorcontrib>Sokumbi, Olayemi</creatorcontrib><title>Pediatric patients with orofacial granulomatosis likely to subsequently develop intestinal Crohn's disease: Brief Report</title><title>Pediatric dermatology</title><addtitle>Pediatr Dermatol</addtitle><description>Orofacial granulomatosis (OFG) is an uncommon chronic granulomatous condition presenting as perioral inflammation in the absence of systemic disease. 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There is continued debate regarding whether OFG is a distinct clinical disorder or a manifestation of orofacial Crohn's disease. Our retrospective review identified 7 patients diagnosed with OFG between 2000 and 2018 at a tertiary pediatric hospital. Four of the 7 patients subsequently developed Crohn's disease with a median delay of 3.1 years (range 0.4‐6.9 years). This indicates that gastroenterology evaluation with long‐term monitoring for intestinal Crohn's disease is warranted.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>32985729</pmid><doi>10.1111/pde.14390</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0002-0361-9234</orcidid><orcidid>https://orcid.org/0000-0003-2869-2718</orcidid></addata></record>
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subjects	Child Crohn Disease - complications Crohn Disease - diagnosis Crohn's disease Dermatology Gastroenterology Granulomatosis Granulomatosis, Orofacial - diagnosis Granulomatosis, Orofacial - drug therapy Granulomatosis, Orofacial - etiology Humans Inflammation Intestine orofacial granulomatosis Patients Pediatrics Retrospective Studies Tertiary Care Centers
title	Pediatric patients with orofacial granulomatosis likely to subsequently develop intestinal Crohn's disease: Brief Report
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