Advanced glycation end products present in the obese uterine environment compromise preimplantation embryo development

Proinflammatory advanced glycation end products (AGE), highly elevated within the uterine cavity of obese women, compromise endometrial function. Do AGE also impact preimplantation embryo development and function? Mouse embryos were cultured in AGE equimolar to uterine fluid concentrations in lean (...

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Veröffentlicht in:	Reproductive biomedicine online 2020-11, Vol.41 (5), p.757-766
Hauptverfasser:	Hutchison, Jennifer C., Truong, Thi T., Salamonsen, Lois A., Gardner, David K., Evans, Jemma
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced glycation end products Implantation Obesity Pregnancy Preimplantation embryo development Trophectoderm
Online-Zugang:	Volltext
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