Anticontractile Effect of Perivascular Adipose Tissue But Not of Endothelium Is Enhanced by Hydrogen Sulfide Stimulation in Hypertensive Pregnant Rat Aortae

Perivascular adipose tissue (PVAT) modulates the vascular tone. Hydrogen sulfide (H2S) is synthetized by cystathionine gamma-lyase (CSE) in brown PVAT. Modulation of vascular contractility by H2S is, in part, adenosine triphosphate (ATP)-sensitive potassium channels dependent. However, the role of P...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2020-12, Vol.76 (6), p.715-729
Hauptverfasser:	Souza-Paula, Edileia, Polonio, Leticia C. C., Zochio, Gabriela P., da Silva, Katiussia Pinho, Kushima, Helio, Dias-Junior, Carlos A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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