Rosmarinic acid improves boar sperm quality, antioxidant capacity and energy metabolism at 17°C via AMPK activation

Boar sperm are susceptible to oxidative damage caused by reactive oxygen species (ROS) during storage. Adenosine monophosphate (AMP)‐activated protein kinase (AMPK) is an important therapeutic target, because it is a cellular metabolism energy sensor and key signalling kinase in spermatozoa. We eval...

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Veröffentlicht in:	Reproduction in domestic animals 2020-12, Vol.55 (12), p.1714-1724
Hauptverfasser:	Feng, Tian‐Yu, Lv, Dong‐Liang, Zhang, Xing, Du, Ye‐Qing, Yuan, Yi‐Tian, Chen, Mei‐Jie, Xi, Hua‐Ming, Li, Yu, Han, Ning, Hu, Jian‐Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine monophosphate Adenosine triphosphate AMP AMP-Activated Protein Kinases - drug effects AMP-Activated Protein Kinases - metabolism AMPK Animals antioxidant Antioxidants Antioxidants - pharmacology ATP boar sperm Cinnamates - pharmacology Damage Depsides - pharmacology Energy Metabolism Fertility Glyceraldehyde Glyceraldehyde-3-phosphate dehydrogenase Integrity Kinases liquid storage Male Malondialdehyde Malondialdehyde - metabolism Membrane potential Membranes Metabolism Mitochondria Phosphorylation Protein kinase Reactive oxygen species Reactive Oxygen Species - metabolism Rosmarinic Acid Semen Analysis - veterinary Semen Preservation - methods Semen Preservation - veterinary Sperm Spermatozoa Spermatozoa - physiology Superoxide dismutase Sus scrofa Zona pellucida
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