Relationship between GFR, intact PTH, oxidized PTH, non‐oxidized PTH as well as FGF23 in patients with CKD

Fibroblast growth factor 23 (FGF23) and parathyroid hormone (PTH) are regulators of renal phosphate excretion and vitamin D metabolism. In chronic kidney disease (CKD), circulating FGF23 and PTH concentrations progressively increase as renal function declines. Oxidation of PTH at two methionine resi...

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Veröffentlicht in:	The FASEB journal 2020-11, Vol.34 (11), p.15269-15281
Hauptverfasser:	Zeng, Shufei, Querfeld, Uwe, Feger, Martina, Haffner, Dieter, Hasan, Ahmed A., Chu, Chang, Slowinski, Torsten, Bernd Dschietzig, Thomas, Schäfer, Franz, Xiong, Yingquan, Zhang, Bingbing, Rausch, Steffen, Horvathova, Katarina, Lang, Florian, Karl Krämer, Bernhard, Föller, Michael, Hocher, Berthold
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Animals Child CKD Female FGF23 Fibroblast Growth Factors - genetics Fibroblast Growth Factors - metabolism GFR Glomerular Filtration Rate Humans Male non‐oxidized Osteoblasts - metabolism Osteoblasts - pathology Oxidation-Reduction oxidized Parathyroid Hormone - chemistry Parathyroid Hormone - metabolism Prospective Studies PTH Rats Renal Insufficiency, Chronic - genetics Renal Insufficiency, Chronic - metabolism Renal Insufficiency, Chronic - pathology
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