BAY61‐3606 protects kidney from acute ischemia/reperfusion injury through inhibiting spleen tyrosine kinase and suppressing inflammatory macrophage response

Acute kidney injury (AKI) is a highly prevalent clinical syndrome with high mortality and morbidity. Previous studies indicated that inflammation promotes tubular damage and plays a key role in AKI progress. Spleen tyrosine kinase (Syk) has been linked to macrophage‐related inflammation in AKI. Up t...

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Veröffentlicht in:	The FASEB journal 2020-11, Vol.34 (11), p.15029-15046
Hauptverfasser:	Tan, Rui‐zhi, Li, Jian‐chun, Liu, Jian, Lei, Xian‐ying, Zhong, Xia, Wang, Chen, Yan, Ying, Linda Ye, Lingyu, Darrel Duan, Dayue, Lan, Hui‐yao, Wang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	AKI BAY61‐3606 macrophage Mincle Syk
Online-Zugang:	Volltext
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