Rapid sequence modification in the highly polymorphic region (HPR) of the hemagglutinin gene of the infectious salmon anaemia virus (ISAV) suggests intra‐segmental template switching recombination

The ISAV has a genome composed of eight segments of (–)ssRNA, segment 6 codes for the hemagglutinin–esterase protein, and has the most variable region of the genome, the highly polymorphic region (HPR), which is unique among orthomyxoviruses. The HPR has been associated with virulence, infectivity a...

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Veröffentlicht in:	Journal of fish diseases 2020-12, Vol.43 (12), p.1483-1496
Hauptverfasser:	Cárdenas, Matías, Galleguillos, Claudia, Acevedo, Karina, Ananias, Catarina, Alarcón, Javiera, Michelson, Sofía, Toledo, Jorge, Montoya, Margarita, Meneses, Claudio, Castro‐Nallar, Eduardo, Vásquez‐Martínez, Yesseny, Cortez‐San Martin, Marcelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaemia Anemia Animals Cell Line Esterase Esterases Fish Diseases - virology Freshwater fishes Genetics Genomes Genotype Genotypes Hemagglutinins Hemagglutinins, Viral - genetics Infectivity ISAV Isavirus - genetics Isavirus - pathogenicity Kidneys Marine fishes Microbiological strains Nucleotide sequence Orthomyxoviridae Orthomyxoviridae Infections - virology Pathogenicity Pathogens recombinant virus Recombinants Recombination Recombination, Genetic Salmo salar Salmon salmonid pathogen Segments Sequence Analysis, DNA Sequencing Switching Variable region Viral Fusion Proteins - genetics Virulence Virulence - genetics Viruses
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