Supplementation of fenugreek with choline–docosahexaenoic acid attenuates menopause induced memory loss, BDNF and dendritic arborization in ovariectomized rats

Cognitive impairment due to natural or surgical menopause is always associated with estrogen deficiency leading to reduced brain-derived neurotrophic factor (BDNF). Reduced BDNF levels in menopause affect neuronal maturation, survival, axonal and dendritic arborization and the maintenance of dendrit...

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Veröffentlicht in:	Anatomical science international 2021-03, Vol.96 (2), p.197-211
Hauptverfasser:	Konuri, Anjaneyulu, Bhat, Kumar M. R., Rai, Kiranmai S., Gourishetti, Karthik, Phaneendra M, Y. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Anatomy Animal Anatomy Animal Physiology Animals Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Breast cancer Cell Biology Choline Cognitive ability Dendritic branching Dendritic spines Dietary supplements Docosahexaenoic acid Docosahexaenoic Acids - pharmacology Estrogens Female Hippocampus Hippocampus - drug effects Hippocampus - metabolism Histology Hormone replacement therapy Human Physiology Medicine Medicine & Public Health Memory Memory - drug effects Memory Disorders - metabolism Menopause Morphology Neuronal Plasticity - drug effects Neurons - drug effects Neurons - metabolism Neurosciences Oophorectomy Original Article Ovariectomy Phytoestrogens Plant Extracts - pharmacology Pyramidal cells Rats Rats, Wistar Thromboembolism Trigonella Trigonella foenum-graecum
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