Comparisons of Edoxaban Versus Warfarin on Levels of Plasma Prothrombin Fragment in Patients With Nonvalvular Atrial Fibrillation

The effect of edoxaban on plasma prothrombin fragment 1+2 (PTF1+2), a sensitive maker of in vivo thrombin generation, has not been fully investigated in nonvalvular atrial fibrillation (NVAF). We compared plasma PTF1+2 levels between 25 NVAF patients receiving warfarin and 100 NVAF patients receivin...

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Veröffentlicht in:	The American journal of cardiology 2020-12, Vol.136, p.71-75
Hauptverfasser:	Tamura, Akira, Yamamoto, Ena, Kawano, Yoshiyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aged, 80 and over Anticoagulants Anticoagulants - therapeutic use Atrial Fibrillation - blood Atrial Fibrillation - complications Cardiac arrhythmia Creatinine Factor Xa Inhibitors - therapeutic use Female Fibrillation Heart failure Humans In vivo methods and tests Independent variables Male Patients Peptide Fragments - blood Plasma Prospective Studies Prothrombin Pyridines - therapeutic use Regression analysis Stroke - etiology Stroke - prevention & control Subgroups Thiazoles - therapeutic use Thrombin Thromboembolism Variables Warfarin Warfarin - therapeutic use
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