Harnessing the bioresponsive adhesion of immuno-bioglue for enhanced local immune checkpoint blockade therapy

Despite the great promise of immune checkpoint blockade (ICB) therapy for cancer treatment, the currently available options for ICB treatment pose major clinical challenges, including the risk of severe systemic autoimmune responses. Here, we developed a novel localized delivery platform, immuno-bio...

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Veröffentlicht in:	Biomaterials 2020-12, Vol.263, p.120380-120380, Article 120380
Hauptverfasser:	Joo, Kye Il, Jeong, Yeonsu, Hwang, Sung-Min, Shin, Mincheol, Lee, Jaeyun, Sharma, Garima, Lee, Haena, Im, Sin-Hyeog, Cha, Hyung Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-PD-L1 Combination cancer immunotherapy Combined Modality Therapy Humans Immune checkpoint blockade Immune Checkpoint Inhibitors Immunotherapy Localized immunotherapy Melanoma - drug therapy Mussel adhesive protein Tumor Microenvironment
Online-Zugang:	Volltext
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