Galectin-3 and acute heart failure: genetic polymorphisms, plasma level, myocardial fibrosis and 1-year outcomes

This study sought to investigate the relationship between galectin-3 (Gal-3), myocardial fibrosis (MF) and outcomes in acute heart failure. The single-nucleotide polymorphisms (SNPs) of at rs4644 and rs4652, plasma Gal-3 level, MF and major adverse events (MAEs) were obtained. There was no significa...

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Veröffentlicht in:	Biomarkers in medicine 2020-08, Vol.14 (11), p.943-954
Hauptverfasser:	Fu, Hao, Nie, Shaoping, Luo, Ping, Ruan, Yang, Zhang, Zichuan, Miao, Huangtai, Li, Xin, Wen, Songnan, Bai, Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease acute heart failure Aged Biomarkers Biomarkers - blood Blood Proteins - genetics Congestive heart failure Ejection fraction Female Fibrosis Fibrosis - blood Fibrosis - genetics Galectin 3 - blood Galectin 3 - genetics Galectin-3 Galectins - blood Galectins - genetics Gene polymorphism Heart failure Heart Failure - blood Heart Failure - genetics Hospitalization Humans major adverse event Male Medical prognosis Middle Aged Mortality myocardial fibrosis Myocardium - metabolism Myocardium - pathology Patients Plasma polymorphism Polymorphism, Single Nucleotide Single-nucleotide polymorphism Software Standard deviation
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