Equine uridine diphospho-glucuronosyltransferase 1A1, 2A1, 2B4, 2B31: cDNA cloning, expression and initial characterization of morphine metabolism

Uridine diphospho-glucuronosyltransferases (UGTs) are membrane-bound enzymes that catalyze the conjugation of glucuronic acid onto a diverse set of xenobiotics. Horses efficiently and extensively glucuronidate a number of xenobiotics, including opioids, making UGTs an important group of drug-metabol...

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Veröffentlicht in:Veterinary anaesthesia and analgesia 2020-11, Vol.47 (6), p.763-772
Hauptverfasser: Hamamoto-Hardman, Briana D., Baden, Russell W., McKemie, Dan S., Knych, Heather K.
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Sprache:eng
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