Impact of notch signaling on the prognosis of patients with head and neck squamous cell carcinoma

•NOTCH1 was frequently expressed in head and neck squamous cell carcinomas (HNSCC).•NOTCH1 expression correlated with HES1 and p21 expression.•NOTCH1/HES1/p21 positive cases had a significantly better prognosis.•Our results suggest a tumor suppressor function for NOTCH signaling in HNSCC. The functi...

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Veröffentlicht in:	Oral oncology 2020-11, Vol.110, p.105003-105003, Article 105003
Hauptverfasser:	Grilli, Gianluigi, Hermida-Prado, Francisco, Álvarez-Fernández, Mónica, Allonca, Eva, Álvarez-González, Miguel, Astudillo, Aurora, Moreno-Bueno, Gema, Cano, Amparo, García-Pedrero, Juana M., Rodrigo, Juan P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Head and neck squamous cell carcinoma HES1 NOTCH1 Prognosis Survival
Online-Zugang:	Volltext
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