Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature
Intracranial capillary hemangiomas (ICHs) are rare vascular tumors composed of a bed of many narrow thin-walled vessels. Within the confines of the skull, these tumors can lead to serious neurologic deficits including cranial nerve dysfunction, mood/personality disturbances, and signs of intracrania...
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Veröffentlicht in: | World neurosurgery 2021-01, Vol.145, p.220-228 |
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creator | Massman, Logan J. Conteh, Fatu Cochran, Elizabeth J. Zwagerman, Nathan T. |
description | Intracranial capillary hemangiomas (ICHs) are rare vascular tumors composed of a bed of many narrow thin-walled vessels. Within the confines of the skull, these tumors can lead to serious neurologic deficits including cranial nerve dysfunction, mood/personality disturbances, and signs of intracranial mass effect.
We report the case of a 23-year-old, 5-week postpartum woman with a history of progressive painful ophthalmalgia of the right eye presenting with rapid onset of ptosis, diplopia, and right-sided facial pain and hypesthesia. Imaging demonstrated a small extraaxial mass within the right cavernous sinus. She underwent 2 operations via an endoscopic endonasal approach for biopsy followed by complete resection. Histology showed a highly mitotic capillary hemangioma, which was negative for both estrogen and progesterone receptors.
We review cases of ICH reported in the literature and provide an updated summary of the presentation, diagnosis, and treatment of ICH. We then present a brief analysis of the reported cases with respect to age and sex.
We conclude that, in experienced hands, the endoscopic endonasal approach can be used to access the cavernous sinus for complete resection of ICHs of the cavernous sinus. We also suggest that further attention be paid to such cases in pregnant and peripartum women as these tumors may progress more quickly in this subpopulation. |
doi_str_mv | 10.1016/j.wneu.2020.09.032 |
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We report the case of a 23-year-old, 5-week postpartum woman with a history of progressive painful ophthalmalgia of the right eye presenting with rapid onset of ptosis, diplopia, and right-sided facial pain and hypesthesia. Imaging demonstrated a small extraaxial mass within the right cavernous sinus. She underwent 2 operations via an endoscopic endonasal approach for biopsy followed by complete resection. Histology showed a highly mitotic capillary hemangioma, which was negative for both estrogen and progesterone receptors.
We review cases of ICH reported in the literature and provide an updated summary of the presentation, diagnosis, and treatment of ICH. We then present a brief analysis of the reported cases with respect to age and sex.
We conclude that, in experienced hands, the endoscopic endonasal approach can be used to access the cavernous sinus for complete resection of ICHs of the cavernous sinus. We also suggest that further attention be paid to such cases in pregnant and peripartum women as these tumors may progress more quickly in this subpopulation.</description><identifier>ISSN: 1878-8750</identifier><identifier>EISSN: 1878-8769</identifier><identifier>DOI: 10.1016/j.wneu.2020.09.032</identifier><identifier>PMID: 32920159</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Cavernous sinus ; Endoscopic endovascular approach ; Intracranial capillary hemangioma ; Peripartum presentation</subject><ispartof>World neurosurgery, 2021-01, Vol.145, p.220-228</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-53da15d966826c3a24aec48bc2fe6c3fab0141c1f4a63d4fda768145e08a02d33</citedby><cites>FETCH-LOGICAL-c422t-53da15d966826c3a24aec48bc2fe6c3fab0141c1f4a63d4fda768145e08a02d33</cites><orcidid>0000-0002-5579-4798</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1878875020320404$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32920159$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Massman, Logan J.</creatorcontrib><creatorcontrib>Conteh, Fatu</creatorcontrib><creatorcontrib>Cochran, Elizabeth J.</creatorcontrib><creatorcontrib>Zwagerman, Nathan T.</creatorcontrib><title>Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature</title><title>World neurosurgery</title><addtitle>World Neurosurg</addtitle><description>Intracranial capillary hemangiomas (ICHs) are rare vascular tumors composed of a bed of many narrow thin-walled vessels. Within the confines of the skull, these tumors can lead to serious neurologic deficits including cranial nerve dysfunction, mood/personality disturbances, and signs of intracranial mass effect.
We report the case of a 23-year-old, 5-week postpartum woman with a history of progressive painful ophthalmalgia of the right eye presenting with rapid onset of ptosis, diplopia, and right-sided facial pain and hypesthesia. Imaging demonstrated a small extraaxial mass within the right cavernous sinus. She underwent 2 operations via an endoscopic endonasal approach for biopsy followed by complete resection. Histology showed a highly mitotic capillary hemangioma, which was negative for both estrogen and progesterone receptors.
We review cases of ICH reported in the literature and provide an updated summary of the presentation, diagnosis, and treatment of ICH. We then present a brief analysis of the reported cases with respect to age and sex.
We conclude that, in experienced hands, the endoscopic endonasal approach can be used to access the cavernous sinus for complete resection of ICHs of the cavernous sinus. We also suggest that further attention be paid to such cases in pregnant and peripartum women as these tumors may progress more quickly in this subpopulation.</description><subject>Cavernous sinus</subject><subject>Endoscopic endovascular approach</subject><subject>Intracranial capillary hemangioma</subject><subject>Peripartum presentation</subject><issn>1878-8750</issn><issn>1878-8769</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLLDEQhYNcUVH_gAvJ0s20eXWm--JGBl8woIhu3ISapNqbYTo9N0kr_nszjLq0NlUF5xw4HyEnnFWccX2-rN4DjpVgglWsrZgUO-SAN9Nm0kx1--fnrtk-OU5pycpIrpqp3CP7UrSC8bo9IC93IUewEYKHFZ3B2q9WED_oLfYQXv3QQ_pLL-kDRr-GmMeePkRMGDJkPwQKwdFHfPP4ToeO5n9I5z5jhDxGPCK7HawSHn_tQ_J8ffU0u53M72_uZpfziVVC5EktHfDatVo3QlsJQgFa1Sys6LD8HSwYV9zyToGWTnUOprrhqkbWABNOykNyts1dx-H_iCmb3ieLpUfAYUxGKCU0Y1q2RSq2UhuHlCJ2Zh19X_oazswGq1maDVazwWpYawrWYjr9yh8XPbofyzfEIrjYCrC0LCyiSdZjsOh8RJuNG_xv-Z9QyImK</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Massman, Logan J.</creator><creator>Conteh, Fatu</creator><creator>Cochran, Elizabeth J.</creator><creator>Zwagerman, Nathan T.</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5579-4798</orcidid></search><sort><creationdate>202101</creationdate><title>Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature</title><author>Massman, Logan J. ; Conteh, Fatu ; Cochran, Elizabeth J. ; Zwagerman, Nathan T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-53da15d966826c3a24aec48bc2fe6c3fab0141c1f4a63d4fda768145e08a02d33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Cavernous sinus</topic><topic>Endoscopic endovascular approach</topic><topic>Intracranial capillary hemangioma</topic><topic>Peripartum presentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Massman, Logan J.</creatorcontrib><creatorcontrib>Conteh, Fatu</creatorcontrib><creatorcontrib>Cochran, Elizabeth J.</creatorcontrib><creatorcontrib>Zwagerman, Nathan T.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>World neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Massman, Logan J.</au><au>Conteh, Fatu</au><au>Cochran, Elizabeth J.</au><au>Zwagerman, Nathan T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature</atitle><jtitle>World neurosurgery</jtitle><addtitle>World Neurosurg</addtitle><date>2021-01</date><risdate>2021</risdate><volume>145</volume><spage>220</spage><epage>228</epage><pages>220-228</pages><issn>1878-8750</issn><eissn>1878-8769</eissn><abstract>Intracranial capillary hemangiomas (ICHs) are rare vascular tumors composed of a bed of many narrow thin-walled vessels. Within the confines of the skull, these tumors can lead to serious neurologic deficits including cranial nerve dysfunction, mood/personality disturbances, and signs of intracranial mass effect.
We report the case of a 23-year-old, 5-week postpartum woman with a history of progressive painful ophthalmalgia of the right eye presenting with rapid onset of ptosis, diplopia, and right-sided facial pain and hypesthesia. Imaging demonstrated a small extraaxial mass within the right cavernous sinus. She underwent 2 operations via an endoscopic endonasal approach for biopsy followed by complete resection. Histology showed a highly mitotic capillary hemangioma, which was negative for both estrogen and progesterone receptors.
We review cases of ICH reported in the literature and provide an updated summary of the presentation, diagnosis, and treatment of ICH. We then present a brief analysis of the reported cases with respect to age and sex.
We conclude that, in experienced hands, the endoscopic endonasal approach can be used to access the cavernous sinus for complete resection of ICHs of the cavernous sinus. We also suggest that further attention be paid to such cases in pregnant and peripartum women as these tumors may progress more quickly in this subpopulation.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>32920159</pmid><doi>10.1016/j.wneu.2020.09.032</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-5579-4798</orcidid></addata></record> |
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subjects | Cavernous sinus Endoscopic endovascular approach Intracranial capillary hemangioma Peripartum presentation |
title | Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature |
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