Adipocytokine dysregulation, abnormal glucose metabolism, and lipodystrophy in HIV-infected adolescents receiving protease inhibitors

•32.5% of PIs-treated adolescents had lipodystrophy: 10% with lipohypertrophy.•87.5% of adolescents with any lipohypertrophy had abnormal glucose metabolism.•Lipoatrophy had similar rate of abnormal glucose metabolism to non-lipodystrophy.•Abnormal adipocytokines were more profound in adolescents wi...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2020-12, Vol.136, p.155145-155145, Article 155145
Hauptverfasser:	Santiprabhob, Jeerunda, Chokephaibulkit, Kulkanya, Khantee, Puttichart, Maleesatharn, Alan, Phonrat, Benjaluck, Phongsamart, Wanatpreeya, Lapphra, Keswadee, Wittawatmongkol, Orasri, Rungmaitree, Supattra, Tanchaweng, Surapong, Maturapat, Sirinoot, Lermankul, Watcharee, Tungtrongchitr, Rungsunn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytokines Adipokines - blood Adiponectin Adolescent Adolescents Adult Blood Glucose - metabolism Cross-Sectional Studies Female Highly active antiretroviral therapy HIV HIV Protease Inhibitors - administration & dosage HIV-1 - metabolism HIV-Associated Lipodystrophy Syndrome - blood HIV-Associated Lipodystrophy Syndrome - drug therapy Humans Insulin resistance Leptin Male Protease inhibitor Resistin
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