Cognitive, adaptive, and behavioral effects of adjunctive rufinamide in Lennox–Gastaut syndrome: A prospective observational clinical study

Lennox–Gastaut syndrome (LGS) is a severe pediatric epilepsy syndrome characterized by multiple drug-resistant seizure types. Children with LGS usually experience cognitive regression, and LGS is almost always associated with moderate to severe cognitive impairment. Rufinamide (RFM) was approved by...

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Veröffentlicht in:	Epilepsy & behavior 2020-11, Vol.112, p.107445-107445, Article 107445
Hauptverfasser:	Operto, Francesca Felicia, Verrotti, Alberto, Marrelli, Alfonso, Ciuffini, Roberta, Coppola, Giangennaro, Pastorino, Grazia Maria Giovanna, Striano, Pasquale, Sole, Michela, Zucca, Claudio, Manfredi, Valentina, Città, Santina, Elia, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anticonvulsants - therapeutic use Child Cognition Cognitive profile Humans Lennox Gastaut Syndrome - drug therapy Lennox–Gastaut syndrome Middle Aged Prospective Studies Rufinamide Triazoles Young Adult
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