Protein succination as a potential surrogate biomarker of airway obstruction. The ilervas project

Airway obstruction (AO) is associated with hypoxemia, systemic inflammation and oxidative stress. These conditions can favor the formation of Advanced Glycation End-products (AGEs) and induce mitochondrial stress. The latter can alter metabolite intermediates in the Krebs cycle leading to the format...

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Veröffentlicht in:	Respiratory medicine 2020-10, Vol.172, p.106124-106124, Article 106124
Hauptverfasser:	González, J., Gracia-Lavedan, E., Pamplona, R., Fernández, E., Lecube, A., de-Torres, J.P., Barbé, F., Torres, G., Benabdelhak, Ikram, Bermúdez, Marcelino, Castro, Eva, de Batlle, Jordi, Colàs-Campàs, Laura, Hernández, Marta, Jové, Mariano, Miquel, Eva, Martínez, Montserrat
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced glycation end-products Advanced glycosylation end products Age Airway management Apoptosis Biobanks Biomarkers Body mass Body mass index Body size Body weight Cardiovascular disease Cholesterol Chronic illnesses Chronic obstructive pulmonary disease Chronology Creatinine Cysteine Diabetes Diet Emphysema Glycosylation Hemoglobin Hypoxemia Intermediates Kidney diseases Krebs cycle Lung diseases Metabolites Mitochondria Mitochondrial metabolic stress Overweight Oxidative stress Proteins Questionnaires Regression analysis Respiratory tract S-(2-succino) cysteine Skin Skin autofluorescence Spirometry Systemic inflammation Tobacco Tricarboxylic acid cycle
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