Safety and Clinical Outcome of Good-Grade Aneurysmal Subarachnoid Hemorrhage in Non-Intensive Care Units
While patients with good grade aneurysmal subarachnoid hemorrhage are routinely admitted in intensive care units, critical care capacity in low-middle income countries (LMICs) is limited. In this study, we report the outcomes of good-grade SAH (Hunt and Hess grades I & II) patients admitted in I...
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Veröffentlicht in: | Journal of stroke and cerebrovascular diseases 2020-10, Vol.29 (10), p.105123-105123, Article 105123 |
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creator | Enriquez, Clare Angeli G. Diestro, Jose Danilo B. Omar, Abdelsimar T. Geocadin, Romergryko G. Legaspi, Gerardo D. |
description | While patients with good grade aneurysmal subarachnoid hemorrhage are routinely admitted in intensive care units, critical care capacity in low-middle income countries (LMICs) is limited. In this study, we report the outcomes of good-grade SAH (Hunt and Hess grades I & II) patients admitted in ICU and non-ICU settings at a center in the Philippines and determine if site of care is predictive of outcome.
We performed a retrospective study of all adults diagnosed with good-grade SAH in a five-year period. Patients were analyzed according to three groups based on site of care: Group A (>50% of length of stay in ICU), Group B (>50% of LOS in non-ICU), and Group C (100% of LOS in non-ICU). The primary outcome measures were in-hospital mortality and mRS score at discharge. The secondary outcome measures were complication rate and LOS.
A total of 242 patients was included in the cohort, which had a mean age of 51.16 years and a female predilection (64%). The rates of in-hospital mortality and favorable functional outcome at discharge were 0.82% and 93.8%, respectively, with no difference across groups. Delayed cerebral ischemia and infection were more frequently diagnosed in ICUs (p < 0.001), while rebleeding occurred more commonly in non-ICUs (p = 0.02). The median LOS was significantly longer in patients who developed complications.
Admission of good-grade aneurysmal SAH patients in non-ICU settings did not adversely affect both in-hospital mortality and functional outcome at discharge. Prospective, randomized studies may lead to changes in pattern of ICU utilization which are critical for LMICs. |
doi_str_mv | 10.1016/j.jstrokecerebrovasdis.2020.105123 |
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We performed a retrospective study of all adults diagnosed with good-grade SAH in a five-year period. Patients were analyzed according to three groups based on site of care: Group A (>50% of length of stay in ICU), Group B (>50% of LOS in non-ICU), and Group C (100% of LOS in non-ICU). The primary outcome measures were in-hospital mortality and mRS score at discharge. The secondary outcome measures were complication rate and LOS.
A total of 242 patients was included in the cohort, which had a mean age of 51.16 years and a female predilection (64%). The rates of in-hospital mortality and favorable functional outcome at discharge were 0.82% and 93.8%, respectively, with no difference across groups. Delayed cerebral ischemia and infection were more frequently diagnosed in ICUs (p < 0.001), while rebleeding occurred more commonly in non-ICUs (p = 0.02). The median LOS was significantly longer in patients who developed complications.
Admission of good-grade aneurysmal SAH patients in non-ICU settings did not adversely affect both in-hospital mortality and functional outcome at discharge. Prospective, randomized studies may lead to changes in pattern of ICU utilization which are critical for LMICs.</description><identifier>ISSN: 1052-3057</identifier><identifier>EISSN: 1532-8511</identifier><identifier>DOI: 10.1016/j.jstrokecerebrovasdis.2020.105123</identifier><language>eng</language><publisher>Elsevier Inc</publisher><subject>Aneurysm clipping ; Aneurysmal subarachnoid hemorrhage ; Critical care ; LMIC</subject><ispartof>Journal of stroke and cerebrovascular diseases, 2020-10, Vol.29 (10), p.105123-105123, Article 105123</ispartof><rights>2020 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-4ae41a673c40c95a6741d897de27c2c85f4cb71c70c2142b77fc765311b4bc1c3</citedby><cites>FETCH-LOGICAL-c381t-4ae41a673c40c95a6741d897de27c2c85f4cb71c70c2142b77fc765311b4bc1c3</cites><orcidid>0000-0001-8450-2021 ; 0000-0001-5177-0521</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2020.105123$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids></links><search><creatorcontrib>Enriquez, Clare Angeli G.</creatorcontrib><creatorcontrib>Diestro, Jose Danilo B.</creatorcontrib><creatorcontrib>Omar, Abdelsimar T.</creatorcontrib><creatorcontrib>Geocadin, Romergryko G.</creatorcontrib><creatorcontrib>Legaspi, Gerardo D.</creatorcontrib><title>Safety and Clinical Outcome of Good-Grade Aneurysmal Subarachnoid Hemorrhage in Non-Intensive Care Units</title><title>Journal of stroke and cerebrovascular diseases</title><description>While patients with good grade aneurysmal subarachnoid hemorrhage are routinely admitted in intensive care units, critical care capacity in low-middle income countries (LMICs) is limited. In this study, we report the outcomes of good-grade SAH (Hunt and Hess grades I & II) patients admitted in ICU and non-ICU settings at a center in the Philippines and determine if site of care is predictive of outcome.
We performed a retrospective study of all adults diagnosed with good-grade SAH in a five-year period. Patients were analyzed according to three groups based on site of care: Group A (>50% of length of stay in ICU), Group B (>50% of LOS in non-ICU), and Group C (100% of LOS in non-ICU). The primary outcome measures were in-hospital mortality and mRS score at discharge. The secondary outcome measures were complication rate and LOS.
A total of 242 patients was included in the cohort, which had a mean age of 51.16 years and a female predilection (64%). The rates of in-hospital mortality and favorable functional outcome at discharge were 0.82% and 93.8%, respectively, with no difference across groups. Delayed cerebral ischemia and infection were more frequently diagnosed in ICUs (p < 0.001), while rebleeding occurred more commonly in non-ICUs (p = 0.02). The median LOS was significantly longer in patients who developed complications.
Admission of good-grade aneurysmal SAH patients in non-ICU settings did not adversely affect both in-hospital mortality and functional outcome at discharge. Prospective, randomized studies may lead to changes in pattern of ICU utilization which are critical for LMICs.</description><subject>Aneurysm clipping</subject><subject>Aneurysmal subarachnoid hemorrhage</subject><subject>Critical care</subject><subject>LMIC</subject><issn>1052-3057</issn><issn>1532-8511</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNqVkD9v2zAQR4UgAfKn-Q4cgwByeRQpymNqtE4AoxnSzAR1PMV0JDIlJQP-9pXhjFk63W94eMC9orgHvgAO9ffdYpfHFN8JKVGb4t5m5_NCcHEEFIjqrLgCVYmyUQDn8-ZKlBVX-rK4znnHOYBq1FWxfbEdjQdmg2Or3gePtmfP04hxIBY7to7RletkHbGHQFM65GEGXqbWJovbEL1jjzTElLb2jZgP7HcM5VMYKWS_J7ayidhr8GP-Vlx0ts90-3lvitdfP_-sHsvN8_pp9bApsWpgLKUlCbbWFUqOSzUvCa5ZakdCo8BGdRJbDag5CpCi1bpDXasKoJUtAlY3xd3J-5Hi34nyaAafkfreBopTNkJKqEHUy2pGf5xQTDHnRJ35SH6w6WCAm2NmszNfZTbHzOaUeZZsThKan9p7Siajp4DkfCIcjYv-f3T_ANPqlQA</recordid><startdate>202010</startdate><enddate>202010</enddate><creator>Enriquez, Clare Angeli G.</creator><creator>Diestro, Jose Danilo B.</creator><creator>Omar, Abdelsimar T.</creator><creator>Geocadin, Romergryko G.</creator><creator>Legaspi, Gerardo D.</creator><general>Elsevier Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8450-2021</orcidid><orcidid>https://orcid.org/0000-0001-5177-0521</orcidid></search><sort><creationdate>202010</creationdate><title>Safety and Clinical Outcome of Good-Grade Aneurysmal Subarachnoid Hemorrhage in Non-Intensive Care Units</title><author>Enriquez, Clare Angeli G. ; Diestro, Jose Danilo B. ; Omar, Abdelsimar T. ; Geocadin, Romergryko G. ; Legaspi, Gerardo D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-4ae41a673c40c95a6741d897de27c2c85f4cb71c70c2142b77fc765311b4bc1c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aneurysm clipping</topic><topic>Aneurysmal subarachnoid hemorrhage</topic><topic>Critical care</topic><topic>LMIC</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Enriquez, Clare Angeli G.</creatorcontrib><creatorcontrib>Diestro, Jose Danilo B.</creatorcontrib><creatorcontrib>Omar, Abdelsimar T.</creatorcontrib><creatorcontrib>Geocadin, Romergryko G.</creatorcontrib><creatorcontrib>Legaspi, Gerardo D.</creatorcontrib><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of stroke and cerebrovascular diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Enriquez, Clare Angeli G.</au><au>Diestro, Jose Danilo B.</au><au>Omar, Abdelsimar T.</au><au>Geocadin, Romergryko G.</au><au>Legaspi, Gerardo D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety and Clinical Outcome of Good-Grade Aneurysmal Subarachnoid Hemorrhage in Non-Intensive Care Units</atitle><jtitle>Journal of stroke and cerebrovascular diseases</jtitle><date>2020-10</date><risdate>2020</risdate><volume>29</volume><issue>10</issue><spage>105123</spage><epage>105123</epage><pages>105123-105123</pages><artnum>105123</artnum><issn>1052-3057</issn><eissn>1532-8511</eissn><abstract>While patients with good grade aneurysmal subarachnoid hemorrhage are routinely admitted in intensive care units, critical care capacity in low-middle income countries (LMICs) is limited. In this study, we report the outcomes of good-grade SAH (Hunt and Hess grades I & II) patients admitted in ICU and non-ICU settings at a center in the Philippines and determine if site of care is predictive of outcome.
We performed a retrospective study of all adults diagnosed with good-grade SAH in a five-year period. Patients were analyzed according to three groups based on site of care: Group A (>50% of length of stay in ICU), Group B (>50% of LOS in non-ICU), and Group C (100% of LOS in non-ICU). The primary outcome measures were in-hospital mortality and mRS score at discharge. The secondary outcome measures were complication rate and LOS.
A total of 242 patients was included in the cohort, which had a mean age of 51.16 years and a female predilection (64%). The rates of in-hospital mortality and favorable functional outcome at discharge were 0.82% and 93.8%, respectively, with no difference across groups. Delayed cerebral ischemia and infection were more frequently diagnosed in ICUs (p < 0.001), while rebleeding occurred more commonly in non-ICUs (p = 0.02). The median LOS was significantly longer in patients who developed complications.
Admission of good-grade aneurysmal SAH patients in non-ICU settings did not adversely affect both in-hospital mortality and functional outcome at discharge. Prospective, randomized studies may lead to changes in pattern of ICU utilization which are critical for LMICs.</abstract><pub>Elsevier Inc</pub><doi>10.1016/j.jstrokecerebrovasdis.2020.105123</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-8450-2021</orcidid><orcidid>https://orcid.org/0000-0001-5177-0521</orcidid></addata></record> |
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subjects | Aneurysm clipping Aneurysmal subarachnoid hemorrhage Critical care LMIC |
title | Safety and Clinical Outcome of Good-Grade Aneurysmal Subarachnoid Hemorrhage in Non-Intensive Care Units |
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