Association between proton pump inhibitor use and mortality in patients with hepatocellular carcinoma receiving tyrosine kinase inhibitor

Discontinuation was defined as a gap of more than 30 days in TKI use after the index date. Since TKI reimbursement was discontinued by Taiwan NHI in patients with disease progression, TKIs discontinuation was used as a surrogate outcome for tumour progression. IPTW adjustment resulted in less signif...

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