Rho GDP-Dissociation Inhibitor 2 Inhibits C-X-C Chemokine Receptor Type 4-Mediated Acute Lymphoblastic Leukemia Cell Migration

Although we currently have a good understanding of the role C-X-C chemokine receptor type 4 (CXCR4) plays in T cell acute lymphoblastic leukemia (T-ALL), the mechanism of CXCR4-mediated T-ALL migration remains elusive. Therefore, we focus on the downstream signals of CXCR4 that contribute to T-ALL c...

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Veröffentlicht in:	Frontiers in oncology 2020-08, Vol.10, p.1512-1512, Article 1512
Hauptverfasser:	Luo, Jixian, Wang, Junting, Zheng, Huiguang, Wang, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	chemokines leukemia Life Sciences & Biomedicine migration Oncology receptor RhoGTPases Science & Technology
Online-Zugang:	Volltext
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